針灸聯(lián)合玻璃酸鈉關(guān)節(jié)腔注射治療膝關(guān)節(jié)炎的臨床療效觀察
發(fā)布時間:2019-01-22 13:00
【摘要】:目的:探究針灸聯(lián)合玻璃酸鈉關(guān)節(jié)腔注射對于膝關(guān)節(jié)炎患者血清細(xì)胞因子的影響,科學(xué)客觀評價兩種方法聯(lián)合應(yīng)用的臨床療效與應(yīng)用價值,改善患者生活質(zhì)量,為臨床治療膝關(guān)節(jié)炎提供安全有效的方法。方法:選取的齊齊哈爾市第二醫(yī)院2012年1月至2013年12月骨外科住院部及門診已經(jīng)被確診為膝關(guān)節(jié)炎的97名患者分成三組,即治療組(針灸結(jié)合玻璃酸鈉組)、對照組Ⅰ(針灸法組)、對照組Ⅱ(膝關(guān)節(jié)腔內(nèi)注射玻璃酸鈉)。三組治療前后均從以下幾個方面進(jìn)行臨床治療療效觀察:(1)膝關(guān)節(jié)疼痛評分情況;(2)膝關(guān)節(jié)功能評分情況;(3)膝關(guān)節(jié)炎患者病情程度評分情況;(4)膝關(guān)節(jié)炎患者臨床治療療效;(5)患者血液中血沉、C-反應(yīng)蛋白濃度。(6)患者血清中IL-1濃度。(7)患者關(guān)節(jié)液中的5-HT濃度。對以上數(shù)據(jù)進(jìn)行采集和檢測,采用SPSS13.0統(tǒng)計軟件,對數(shù)據(jù)進(jìn)行統(tǒng)計學(xué)分析,進(jìn)而得出結(jié)論。結(jié)果:膝關(guān)節(jié)各項評分情況:三組患者在治療前膝關(guān)節(jié)疼痛評分、功能評分、病情程度評分均無統(tǒng)計學(xué)差異(P0.05);治療后,各組與其治療前相比,評分均存在統(tǒng)計學(xué)差異(P0.05),且治療后,治療組評分高于對照組Ⅰ和對照組Ⅱ(P0.05)。臨床治療效果:三組的治療效果具有統(tǒng)計學(xué)差異(P0.05),治療組有效率高于其他各組,且有效例數(shù)最多。臨床常規(guī)檢查結(jié)果:三組患者在治療前血沉、C反應(yīng)蛋白濃度差異無統(tǒng)計學(xué)意義(P0.05);治療后,各組與其治療前相比,血沉、C反應(yīng)蛋白濃度差異具有統(tǒng)計學(xué)意義(P0.05);治療后,治療組血沉、C反應(yīng)蛋白濃度低于對照組Ⅰ和對照組Ⅱ,具有統(tǒng)計學(xué)意義(P0.05)。血清中細(xì)胞因子檢驗結(jié)果:三組患者在治療前血清IL-1、5-HT濃度無統(tǒng)計學(xué)意義(P0.05);治療后,各組與其治療前相比,血清IL-1及5-HT濃度差異均存在統(tǒng)計學(xué)意義(P0.05);治療后,治療組血清IL-1、5-HT濃度低于對照組Ⅰ和對照組Ⅱ,具有統(tǒng)計學(xué)意義(P0.05)。結(jié)論:1.針灸聯(lián)合玻璃酸鈉膝關(guān)節(jié)腔注射療法對膝骨關(guān)節(jié)炎疼痛、功能活動的臨床療效顯著,能夠明顯減輕患者膝關(guān)節(jié)炎的病情,優(yōu)于單純針灸或單純玻璃酸鈉膝關(guān)節(jié)腔注射療法。2.針灸聯(lián)合玻璃酸鈉膝關(guān)節(jié)腔注射可有效降低膝骨關(guān)節(jié)炎患者血清IL-1、5-HT濃度,阻遏炎癥的進(jìn)一步發(fā)展,且療效明顯優(yōu)于單純針灸和單純純玻璃酸鈉膝關(guān)節(jié)腔注射療法。3.針灸聯(lián)合玻璃酸鈉膝關(guān)節(jié)腔注射療法對KOA的臨床療效優(yōu)于單獨針灸或玻璃酸鈉膝關(guān)節(jié)腔注射。4.針灸聯(lián)合玻璃酸鈉膝關(guān)節(jié)腔注射療法在治療膝骨關(guān)節(jié)試驗中未發(fā)生不良反應(yīng),該療法安全有效。針灸聯(lián)合玻璃酸鈉注射對于治療膝關(guān)節(jié)炎患者具有良好的臨床療效,能夠較快的減少患者膝關(guān)節(jié)疼痛,改善患者膝關(guān)節(jié)活動度等臨床上的病癥,具有一定的臨床意義,值得進(jìn)一步推廣。
[Abstract]:Objective: to investigate the effect of acupuncture and moxibustion combined with sodium hyaluronate injection on serum cytokines in patients with knee arthritis, to evaluate scientifically and objectively the clinical efficacy and application value of the two methods, and to improve the quality of life of the patients. To provide a safe and effective method for the clinical treatment of knee arthritis. Methods: from January 2012 to December 2013, 97 patients who had been diagnosed as knee arthritis were divided into three groups: treatment group (acupuncture combined with sodium hyaluronate). Control group 鈪,
本文編號:2413229
[Abstract]:Objective: to investigate the effect of acupuncture and moxibustion combined with sodium hyaluronate injection on serum cytokines in patients with knee arthritis, to evaluate scientifically and objectively the clinical efficacy and application value of the two methods, and to improve the quality of life of the patients. To provide a safe and effective method for the clinical treatment of knee arthritis. Methods: from January 2012 to December 2013, 97 patients who had been diagnosed as knee arthritis were divided into three groups: treatment group (acupuncture combined with sodium hyaluronate). Control group 鈪,
本文編號:2413229
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