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后路經(jīng)單側(cè)椎弓根入路病灶清除植骨內(nèi)固定治療胸腰椎結(jié)核的療效分析

發(fā)布時間:2018-12-12 03:34
【摘要】:目的探討后路經(jīng)單側(cè)椎弓根入路病灶清除、植骨融合、椎弓根螺釘內(nèi)固定術(shù)治療胸腰椎結(jié)核的臨床療效。方法2010年1月~2014年1月,我科共收治胸腰椎結(jié)核患者174例,滿足納入標準者共97例,A組(治療組,53例)接受經(jīng)單側(cè)椎弓根入路病灶清除植內(nèi)固定術(shù)治療,B組(對照組,44例)接受傳統(tǒng)后路病灶清除植骨內(nèi)固定術(shù)治療。通過A、B組的對比分析來評估單側(cè)椎弓入路病灶清除植骨內(nèi)固定術(shù)治療胸腰椎結(jié)核的臨床療效。結(jié)果兩組患者均安全度過圍手術(shù)期,隨訪12~48個月,術(shù)后臨床癥狀緩解滿意,血沉、CRP恢復正常,術(shù)后X線片提示后凸畸形矯正滿意,術(shù)后3-9個月椎間植骨達骨性融合,末次隨訪后凸Cobb角較術(shù)后無明顯丟失,神經(jīng)功能Frankel分級提高0-2級。A、B組患者組間比較:手術(shù)時間、術(shù)中出血量、術(shù)后住院時間、術(shù)后Cobb角丟失、VAS評分無明顯差異(P0.05);A組術(shù)后引流量明顯少于B組(P0.05);A組術(shù)后第3個月ODI指數(shù)明顯低于B組(P0.05),兩組ODI指數(shù)末次隨訪無統(tǒng)計學差異(P0.05);A、B組術(shù)前及末次隨訪Frankel分級無明顯差異(P0.05)。A組1例患者術(shù)后1月出現(xiàn)腰大肌膿腫,經(jīng)膿腫清除后痊愈,其余無內(nèi)固定松動、斷裂等并發(fā)癥發(fā)生。結(jié)論采用經(jīng)單側(cè)椎弓根入路病灶清除、植骨融合、椎弓根螺釘內(nèi)固定術(shù)治療胸腰椎結(jié)核,臨床療效滿意,相比于傳統(tǒng)后路手術(shù)創(chuàng)傷更小,脊柱的穩(wěn)定性更強,術(shù)后功能恢復更快。
[Abstract]:Objective to investigate the clinical effect of posterior transpedicular approach for the treatment of thoracolumbar tuberculosis. Methods from January 2010 to January 2014, 174 patients with thoracolumbar tuberculosis were treated in our department, 97 of whom met the inclusion criteria. Group A (treatment group, 53 cases) received unilateral pedicle approach, and group B (control group) received unilateral pedicle debridement and internal fixation. 44 cases were treated with traditional posterior debridement, bone grafting and internal fixation. To evaluate the clinical effect of unilateral pedicle debridement, bone grafting and internal fixation for thoracolumbar tuberculosis. Results the patients in both groups survived the perioperative period safely and were followed up for 12 ~ 48 months. The clinical symptoms were satisfactory, the erythrocyte sedimentation rate and CRP returned to normal, the X-ray film showed that the correction of kyphosis was satisfactory, and the intervertebral bone graft reached bone fusion 3-9 months after operation. There was no significant loss of kyphosis Cobb angle after the last follow-up, and the Frankel grade of nerve function was increased by 0-2 grades. The time of operation, the amount of blood lost during operation, the time of hospitalization after operation, the loss of Cobb angle after operation in group A were compared. There was no significant difference in VAS score (P0.05). The postoperative drainage volume in group A was significantly lower than that in group B (P0.05). The ODI index in group); A was significantly lower than that in group B (P0.05). There was no significant difference in ODI index between the two groups at the last follow-up (P0.05). There was no significant difference in Frankel grade before and at the last follow-up in group A (P0.05). One patient in group). A had abscess of psoas major muscle one month after operation, which was cured after abscess removal, and no complications such as loosening of internal fixation and fracture occurred. Conclusion the treatment of thoracolumbar tuberculosis by unilateral pedicle approach with debridement, bone graft fusion and pedicle screw fixation is satisfactory. Compared with the traditional posterior approach, the trauma is less and the spine is more stable. The function recovered more quickly after operation.
【學位授予單位】:重慶醫(yī)科大學
【學位級別】:碩士
【學位授予年份】:2015
【分類號】:R687.3

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