發(fā)布時間：2018-11-25 07:27

【摘要】：目的探討甲狀腺清潔手術(shù)圍手術(shù)期不預(yù)防性應(yīng)用抗菌藥物的安全性,為臨床治療提供參考依據(jù)。方法選擇2015年1月-2016年1月醫(yī)院行甲狀腺清潔手術(shù)患者1 024例作為研究對象,根據(jù)患者圍手術(shù)期是否應(yīng)用抗菌藥物分為觀察組784例和對照組240例;觀察比較兩組患者臨床指標。結(jié)果兩組患者的術(shù)后感染率比較差異無統(tǒng)計學(xué)意義;兩組術(shù)后1天和術(shù)后3天發(fā)熱比例比較差異均無統(tǒng)計學(xué)意義;兩組術(shù)后1天和術(shù)后3天體溫比較差異均無統(tǒng)計學(xué)意義;兩組患者術(shù)后血白細胞計數(shù)和中性粒細胞比例比較差異沒有統(tǒng)計學(xué)意義;兩組患者術(shù)后傷口引流時間、住院天數(shù)比較差異均無統(tǒng)計學(xué)意義。結(jié)論甲狀腺清潔手術(shù)圍手術(shù)期不預(yù)防性應(yīng)用抗菌藥物并不增加感染的概率,甲狀腺清潔手術(shù)圍手術(shù)期不預(yù)防性應(yīng)用抗菌藥物是安全的。
[Abstract]:Objective to explore the safety of non-prophylactic use of antimicrobial agents in the perioperative period of clean thyroid surgery and to provide reference for clinical treatment. Methods from January 2015 to January 2016, 1 024 patients undergoing thyroid cleaning operation were divided into observation group (784 cases) and control group (240 cases). The clinical indexes of the two groups were observed and compared. Results there was no significant difference in the postoperative infection rate between the two groups, there was no significant difference in the febrile ratio between the two groups on the 1st day and the 3rd day after operation, and there was no significant difference in body temperature between the two groups on the 1st and 3rd day after operation. There was no significant difference in blood leukocyte count and neutrophil ratio between the two groups, but there was no significant difference in postoperative wound drainage time and hospital stay between the two groups. Conclusion the non-prophylactic use of antimicrobial agents in the perioperative period of thyroid cleaning surgery does not increase the probability of infection, and it is safe to use antimicrobial agents in the perioperative period of thyroid cleaning surgery.
【作者單位】： 寧波市第二醫(yī)院甲狀腺外科;
【基金】：2014年浙江省醫(yī)藥衛(wèi)生一般研究計劃項目(2014KYB038)
【分類號】：R653

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