【摘要】：目的:觀察苦柏顆粒洗劑對(duì)濕熱下注型低位單純性肛瘺術(shù)后愈合的臨床療效,為其臨床推廣應(yīng)用提供理論依據(jù)。方法:將符合診斷標(biāo)準(zhǔn)采用低位單純性肛瘺切除術(shù)的60例患者隨機(jī)分為兩組,治療組和對(duì)照組各30例。進(jìn)行21天療程對(duì)比治療,其中治療組以苦柏顆粒洗劑治療,對(duì)照組以痔疾洗液治療。在治療結(jié)束后進(jìn)行臨床療效評(píng)價(jià),比較前后兩組的患者創(chuàng)面疼痛、滲液情況及創(chuàng)面肉芽組織生長(zhǎng)情況,并做出評(píng)分,然后應(yīng)用spss17.0系統(tǒng)軟件進(jìn)行統(tǒng)計(jì)學(xué)分析。結(jié)果:選定病例后,在兩組對(duì)比治療前,對(duì)患者的年齡、性別、病程、術(shù)后創(chuàng)面情況、疼痛、創(chuàng)面分泌物及創(chuàng)面肉芽組織生長(zhǎng)情況等進(jìn)行比較,差異均無(wú)統(tǒng)計(jì)學(xué)意義,具有可比性。研究結(jié)果分析如下:(1)疼痛評(píng)分比較:兩組術(shù)后第3天和第7天患者創(chuàng)面疼痛狀況有統(tǒng)計(jì)學(xué)意義(P0.05),治療組評(píng)分優(yōu)于對(duì)照組。第14天和第21天疼痛狀況無(wú)明顯差異,無(wú)統(tǒng)計(jì)學(xué)意義(P0.05)。(2)創(chuàng)面分泌物:兩組術(shù)后第3天、第7天檢查創(chuàng)面所敷紗布情況并記錄沾染紗布層數(shù),進(jìn)行分泌物比較,差別均有統(tǒng)計(jì)學(xué)意義(P0.05),治療組創(chuàng)面分泌物評(píng)分優(yōu)于對(duì)照組。術(shù)后第14天、第21天,觀察組創(chuàng)面分泌物計(jì)分比較,P0.05,差異無(wú)統(tǒng)計(jì)學(xué)意義。(3)創(chuàng)面肉芽組織生長(zhǎng)情況:治療后第7天評(píng)分比較,兩組差異無(wú)統(tǒng)計(jì)學(xué)意義(P0.05)。治療后第14天、第21天評(píng)分比較兩組差異均具有統(tǒng)計(jì)學(xué)意義(P0.05),兩組相比較治療組優(yōu)于對(duì)照組。(4)總療效和創(chuàng)面愈合時(shí)間:兩組患者治療后均痊愈,治療組平均創(chuàng)面愈合時(shí)間為19.13±2.63天;對(duì)照組平均創(chuàng)面愈合時(shí)間為20.27±2.38天。結(jié)果:兩組平均創(chuàng)面愈時(shí)間比較差異有統(tǒng)計(jì)學(xué)意義(P0.05),治療組明顯優(yōu)于對(duì)照組。結(jié)論:苦柏顆粒洗劑可以顯著減輕濕熱下注型低位單純性肛瘺患者術(shù)后創(chuàng)面的疼痛,減少創(chuàng)面滲出,促進(jìn)創(chuàng)面肉芽組織生長(zhǎng),加快創(chuàng)面愈合。
[Abstract]:Objective: to observe the clinical effect of Kubai granule lotion on the healing of low grade anal fistula with damp-heat injection, and to provide theoretical basis for its clinical application. Methods: 60 patients with low simple anal fistula were randomly divided into two groups: treatment group (n = 30) and control group (n = 30). The treatment group was treated with Kubai granule lotion and the control group was treated with hemorrhoid lotion. At the end of the treatment, the clinical efficacy was evaluated, and the wound pain, exudation and granulation tissue growth were compared before and after the treatment. Then the spss17.0 system software was used for statistical analysis. Results: there was no significant difference in age, sex, course of disease, postoperative wound condition, pain, wound secretion and granulation tissue growth between the two groups. Comparable. The results of the study were as follows: (1) comparison of pain scores: the pain status of the patients in the treatment group was significantly higher than that in the control group on the 3rd and 7th day after operation (P0.05). There was no significant difference in pain status between day 14 and day 21 (P0.05). (2): on the 3rd and 7th day after operation, the wound gauze was examined and the number of coated gauze layers was recorded, and the secretion was compared between the two groups. The difference was statistically significant (P0.05). The score of wound secretion in the treatment group was better than that in the control group. On the 14th and 21st day after operation, the score of wound secretion in the observation group was not statistically significant (P 0.05). (3) the granulation tissue growth of the wound: the score was not significantly different between the two groups on the 7th day after treatment (P0.05). On the 14th day and 21st day after treatment, the scores of the two groups were significantly different (P0.05). The treatment group was better than the control group. (4) the total curative effect and wound healing time: the two groups were cured after treatment. The average wound healing time in the treatment group was 19.13 鹵2.63 days. The average wound healing time in the control group was 20.27 鹵2.38 days. Results: the average wound healing time of the two groups was significantly different (P0.05), the treatment group was significantly better than the control group. Conclusion: Kubai granule lotion can significantly reduce the pain of the wound, reduce the exudation of the wound, promote the growth of granulation tissue and accelerate the wound healing.
【學(xué)位授予單位】：黑龍江省中醫(yī)藥科學(xué)院
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2017
【分類號(hào)】：R657.16

【參考文獻(xiàn)】

相關(guān)期刊論文 前10條

1 聞?dòng)?李俊;龍慶;林丹;;不同頻次和時(shí)機(jī)的中藥坐浴對(duì)于痔術(shù)后并發(fā)癥的影響[J];湖南中醫(yī)雜志;2016年12期

2 王建萍;易滿;洪玉芬;潘芳杰;;肛腸病術(shù)后傷口氧療促進(jìn)傷口愈合的臨床研究[J];新疆中醫(yī)藥;2016年05期

3 文建珍;;頭孢西丁預(yù)防確定性肛瘺切除術(shù)術(shù)后手術(shù)部位感染的隨機(jī)對(duì)照研究[J];中國(guó)醫(yī)院用藥評(píng)價(jià)與分析;2016年S1期

4 孫鳳偉;;加味苦參湯坐浴熏洗對(duì)緩解肛瘺術(shù)后創(chuàng)面疼痛及促進(jìn)愈合的效果觀察[J];現(xiàn)代中西醫(yī)結(jié)合雜志;2015年36期

5 陳蓉蓉;蔡而瑋;;賽霉安散對(duì)低位單純性肛瘺術(shù)后創(chuàng)面愈合影響研究[J];亞太傳統(tǒng)醫(yī)藥;2015年23期

6 陳瑞波;;重組人表皮生長(zhǎng)因子凝膠對(duì)肛瘺術(shù)后創(chuàng)面愈合的臨床療效觀察[J];中國(guó)現(xiàn)代醫(yī)生;2015年18期

7 劉芬;劉艷菊;田春漫;;蒼術(shù)麩炒前后對(duì)脾虛證大鼠免疫系統(tǒng)及胃腸激素的影響[J];上海交通大學(xué)學(xué)報(bào)(醫(yī)學(xué)版);2015年01期

8 蘇瑞;李玲;徐宏彬;;復(fù)方苦參注射液對(duì)胃腸道惡性腫瘤輔助治療的臨床觀察[J];中國(guó)醫(yī)院藥學(xué)雜志;2015年04期

9 劉劍剛;;中醫(yī)掛線配合中藥熏洗治療復(fù)雜性肛瘺的療效分析[J];職業(yè)衛(wèi)生與病傷;2014年06期

10 楊磊;張延英;李卉;萬(wàn)學(xué)中;吳建軍;;黃柏煎劑的抗炎、抗菌作用研究[J];實(shí)驗(yàn)動(dòng)物科學(xué);2014年04期

相關(guān)碩士學(xué)位論文 前4條

1 李旭杰;復(fù)方龍血竭散促進(jìn)濕熱下注型肛瘺創(chuàng)面愈合的臨床研究[D];浙江中醫(yī)藥大學(xué);2016年

2 徐銘澤;苦參生物堿分離純化工藝研究[D];哈爾濱商業(yè)大學(xué);2015年

3 葉道冰;清熱生肌洗劑促進(jìn)低位單純性肛瘺術(shù)后創(chuàng)面愈合臨床研究[D];河南中醫(yī)學(xué)院;2015年

4 林偉亮;象皮生肌膏促進(jìn)低位單純性肛瘺術(shù)后創(chuàng)面愈合的臨床療效觀察[D];湖南中醫(yī)藥大學(xué);2014年

，

本文編號(hào)：2344843