肝臟切除術(shù)后肝淤血對早期殘肝再生、肝功能恢復的影響
發(fā)布時間:2018-11-17 09:14
【摘要】:目的觀察肝切除術(shù)后肝臟淤血時對早期殘肝再生及術(shù)后肝功能恢復的影響。方法:2012年1月至2014年10月期間,我院32例肝癌患者,均實施右半肝切除術(shù),術(shù)后根據(jù)觀察將其分為實驗組(因腫瘤侵犯肝中靜脈或術(shù)中肝中靜脈損傷致無法修補、重建造成肝Ⅳ段淤血,12例)和對照組(行保留肝中靜脈的右半肝切除,術(shù)后殘肝未發(fā)生淤血,20例)。通過IQQA-LIVER對兩組患者術(shù)前和術(shù)后兩周時的肝臟進行三維重建,并結(jié)合術(shù)中水測法計算出殘肝再生率,進行殘肝再生率的比較;自動生化分析儀檢測術(shù)后第1、3、5、7天肝臟生化指標(血漿AST、ALT、TBIL水平);ELISA法檢測術(shù)后第1、3、5、7天血清HGF、VEGF水平;術(shù)后兩周時兩組ICGR15測定;術(shù)后并發(fā)癥的觀察。結(jié)果:1.術(shù)后兩周時兩組患者的總體肝再生率相比,結(jié)果無統(tǒng)計學差異(P0.05)。2.兩組患者術(shù)后第1、3、5、7天肝臟生化指標(ALT、AST、TBIL)相比,差異無統(tǒng)計學意義(P0.05)。3.與無淤血組相比,淤血組術(shù)后第1、3、5、7天血清HGF、VEGF水平都沒有出現(xiàn)明顯變化,差異無統(tǒng)計學意義(P0.05)。4.術(shù)后兩周時兩組患者的ICGR15比較,結(jié)果有統(tǒng)計學差異(P0.05)。5.術(shù)后兩組患者都沒有出現(xiàn)嚴重并發(fā)癥。結(jié)論:淤血對肝切除術(shù)后殘肝再生及肝功能的恢復沒有影響。
[Abstract]:Objective to observe the effect of liver congestion after hepatectomy on early residual liver regeneration and postoperative liver function recovery. Methods: from January 2012 to October 2014, 32 patients with liver cancer in our hospital underwent right hemihepatectomy. According to the observation, they were divided into two groups: the experimental group (which could not be repaired due to tumor invading the middle hepatic vein or the injury of the middle hepatic vein during operation). There were 12 cases of hepatic 鈪,
本文編號:2337258
[Abstract]:Objective to observe the effect of liver congestion after hepatectomy on early residual liver regeneration and postoperative liver function recovery. Methods: from January 2012 to October 2014, 32 patients with liver cancer in our hospital underwent right hemihepatectomy. According to the observation, they were divided into two groups: the experimental group (which could not be repaired due to tumor invading the middle hepatic vein or the injury of the middle hepatic vein during operation). There were 12 cases of hepatic 鈪,
本文編號:2337258
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