切開掛線聯(lián)合甲硝唑與左氧氟沙星對肛周膿腫感染患者病原菌及血漿內(nèi)毒素水平的影響
[Abstract]:Objective to analyze the effect of incision and thread combined with metronidazole and levofloxacin on plasma endotoxin level and pathogenic bacteria in patients with perianal abscess infection. Methods from September 2015 to September 2016, 70 patients with perianal abscess infection were selected. According to the principles of randomized, controlled and double-blind trials, they were divided into two groups, 35 cases in each group. The patients in the control group were treated with metronidazole combined with levofloxacin. On the basis of the treatment in the control group, the patients in the experimental group were treated with incision and thread, and the pathogenic bacteria, plasma endotoxin, effective rate and recurrence rate were observed and analyzed. Results after treatment, the number of fungi, Staphylococcus aureus and Escherichia coli in the experimental group was lower than that in the control group (P0.05), and the plasma endotoxin level in the experimental group was lower than that in the control group (P0.05). The total effective rate of treatment in the trial group was 91.43, which was higher than that in the control group (68.57%) (P0.05), and the recurrence rate in the trial group was 2.86%, lower than that in the control group (11.43%) (P0.05). Conclusion for the patients with perianal abscess infection, the treatment of incision combined with metronidazole and levofloxacin is beneficial to improve the number of pathogenic bacteria around the anus, prevent the increase of plasma endotoxin level, improve the clinical treatment effect and reduce the recurrence rate. It is worth popularizing and applying in clinic.
【作者單位】: 齊河縣人民醫(yī)院普外科;
【基金】:山東省自然科學(xué)基金資助項(xiàng)目(ZR2009CL018)
【分類號】:R446.5;R657.15
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