發(fā)布時(shí)間：2018-10-05 14:10

【摘要】：目的分析骨質(zhì)疏松性椎體壓縮骨折球囊擴(kuò)張椎體后凸成形(PKP)術(shù)后繼發(fā)相鄰節(jié)段椎體骨折的危險(xiǎn)因素。方法選取2006-03—2013-07在本院行PKP治療并獲得1年以上隨訪,且自愿參與課題的135例骨質(zhì)疏松性椎體壓縮骨折患者作為研究對(duì)象。根據(jù)隨訪結(jié)果有無出現(xiàn)繼發(fā)相鄰節(jié)段椎體新鮮骨折,將研究對(duì)象分為骨折組(28例)和對(duì)照組(107例)。觀察記錄2組性別、年齡、BMI指數(shù)、骨密度、術(shù)前傷椎個(gè)數(shù)、手術(shù)前后Cobb角,以及骨水泥量、骨水泥注射方法(單或雙側(cè)注射)、有無骨水泥滲漏、傷椎前緣高度恢復(fù)程度。結(jié)果多因素Logistic回歸分析結(jié)果發(fā)現(xiàn)低BMI指數(shù)、低骨密度、傷椎個(gè)數(shù)多、骨水泥發(fā)生滲漏是引起PKP術(shù)后繼發(fā)相鄰節(jié)段椎體再骨折的危險(xiǎn)因素,差異有統(tǒng)計(jì)學(xué)意義(P0.05)。其中低骨密度和骨水泥滲漏是最主要的危險(xiǎn)因素。結(jié)論低骨密度和骨水泥滲漏是引起骨質(zhì)疏松性椎體壓縮骨折PKP術(shù)后繼發(fā)相鄰節(jié)段椎體骨折的主要危險(xiǎn)因素,完善術(shù)前準(zhǔn)備和堅(jiān)持抗骨質(zhì)疏松治療是主要預(yù)防措施。
[Abstract]:Objective to analyze the risk factors of secondary adjacent vertebral body fracture after (PKP) with balloon dilation of osteoporotic vertebral body compression fracture. Methods 135 patients with osteoporotic vertebral compression fractures who received PKP treatment in our hospital from March to July 2006 and who had been followed up for more than one year were selected as the study objects. According to the results of follow-up, the subjects were divided into two groups: fracture group (n = 28) and control group (n = 107). Sex, age and BMI index, bone mineral density (BMD), the number of injured vertebrae before and after operation, the Cobb angle before and after operation, the amount of bone cement, the method of cement injection (single or bilateral injection), the degree of bone cement leakage and the degree of recovery of the anterior edge height of the injured vertebrae were observed and recorded. Results the results of multivariate Logistic regression analysis showed that low BMI index, low bone density, large number of injured vertebrae, bone cement leakage were the risk factors of secondary adjacent vertebral body refracture after PKP, the difference was statistically significant (P0.05). Low bone mineral density and bone cement leakage are the main risk factors. Conclusion low bone mineral density and cement leakage are the main risk factors for the secondary adjacent vertebral body fracture after PKP. The main preventive measures are to perfect preoperative preparation and adhere to anti-osteoporosis treatment.
【作者單位】： 深圳市寶安區(qū)福永人民醫(yī)院骨科;
【基金】：深圳市寶安區(qū)科技計(jì)劃項(xiàng)目(2012111)
【分類號(hào)】：R687.3

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