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人工關(guān)節(jié)假體與宿主骨接觸面積的研究

發(fā)布時間:2018-09-12 17:38
【摘要】:人工髖關(guān)節(jié)置換術(shù)成功在臨床上應(yīng)用之后,術(shù)后導(dǎo)致的臨床并發(fā)癥一直被人們廣泛關(guān)注。最常見的后遺癥就是假體的無菌性松動及下沉。引發(fā)此問題的原因非常多,像假體規(guī)格尺寸、手術(shù)過程中的人為因素、假體附近出現(xiàn)的骨骼溶解以及骨疏松等等。人工關(guān)節(jié)假體和其宿主骨接觸面積的大小直接決定了關(guān)節(jié)假體和宿主骨二者負(fù)重的傳遞及分布,它在判斷假體是否松動下沉及其是否可以長久固定有至關(guān)重要的作用。本文以人工關(guān)節(jié)假體C T圖像為數(shù)據(jù)源,在對圖像進(jìn)行處理的基礎(chǔ)上,計算假體與宿主骨的接觸面積,分析接觸面積大小對關(guān)節(jié)假體松動的影響,幫助醫(yī)生判斷假體的穩(wěn)定性,及早確定假體的松動狀況,為后續(xù)治療提供可靠的依據(jù)。本文主要從以下幾個展開研究工作:1.醫(yī)學(xué)圖像的預(yù)處理:患者攜帶的金屬物體會引起C T重建圖像中出現(xiàn)金屬偽影,嚴(yán)重影響圖像質(zhì)量。金屬偽影對后續(xù)圖像三維重建以及接觸面積的計算會產(chǎn)生直接或間接的影響,圖像中偽影的去除不可或缺。本文找到了一種基于K均值聚類與迭代修正的C T金屬偽影去除算法。首先,利用于K均值聚類法分割出金屬,并結(jié)合線性插值修正投影數(shù)據(jù),得到一張預(yù)處理圖像,接著以此為基礎(chǔ)進(jìn)行迭代校正,迭代處理時通過各向異性平滑濾波來優(yōu)化圖像質(zhì)量,通過多次迭代后得到目標(biāo)圖像。實(shí)驗(yàn)表明,相比于傳統(tǒng)的分割和插值方法,本文方法能夠更加準(zhǔn)確的分割出金屬物體和有效的去除金屬偽影,且不會引入新的條紋偽影。2.醫(yī)學(xué)圖像的三維重建:在對醫(yī)學(xué)圖像進(jìn)行重建的過程中傳統(tǒng)三維面繪制移動立方體(M C)算法速度很緩慢、組織分離比較難,本文提出了一種改進(jìn)的移動立方體算法。該算法根據(jù)人體器官相連的特征,首先挑選一些種子體元,然后依據(jù)這些種子衍生出器官全部等值面,從而減少了對沒用體元的搜尋;同時,通過n次等分點(diǎn)法代替線性插值求解法向量和等值點(diǎn)坐標(biāo),縮減了運(yùn)算次數(shù)。提高了算法的執(zhí)行效率。重建出人工關(guān)節(jié)假體與宿主骨三維模型。為接觸面積的計算奠定基礎(chǔ)。3.接觸面積的計算:在三維重建模型的基礎(chǔ)上,通過結(jié)合有限元接觸分析理論和網(wǎng)格劃分軟件求出接觸面積。算法將建立好的三維模型以I G S格式導(dǎo)入到網(wǎng)格劃分軟件H y p e r m e s h 1 0.0中,對模型進(jìn)行網(wǎng)格劃分。并在有限元接觸分析的基本理論上將假體和股骨接觸部分的網(wǎng)格節(jié)點(diǎn)一一對應(yīng),計算出網(wǎng)格的節(jié)點(diǎn)數(shù)和單元數(shù),進(jìn)而估算出接觸面積。并通過對假體與宿主骨不同接觸區(qū)域面積大小的計算,討論接觸面積大小與松動的關(guān)系。具有較強(qiáng)的臨床意義和價值。
[Abstract]:After the successful application of artificial hip arthroplasty, the postoperative complications have been paid more and more attention. The most common sequelae are aseptic loosening and sinking of the prosthesis. There are many reasons for this problem, such as the size of the prosthesis, artificial factors during the operation, bone dissolution near the prosthesis, and osteoporosis and so on. The size of the contact area between the prosthesis and its host bone directly determines the weight transfer and distribution between the prosthesis and the host bone. It plays an important role in judging whether the prosthesis is loosening and sinking and whether the prosthesis can be fixed for a long time. Based on the CT image of artificial joint prosthesis, the contact area between prosthesis and host bone is calculated, and the influence of contact area on the loosening of prosthesis is analyzed to help doctors judge the stability of prosthesis. To determine the loosening condition of prosthesis as early as possible, and to provide reliable basis for subsequent treatment. This article mainly starts the research work from the following several. Medical image preprocessing: metal objects carried by patients will cause metal artifacts in CT reconstruction images, which seriously affect the image quality. Metal artifacts have a direct or indirect effect on the 3D reconstruction and the calculation of contact area, so the removal of artifacts is indispensable. In this paper, an algorithm for removing artifacts of C T metal based on K-means clustering and iterative correction is found. Firstly, the metal is segmented by K-means clustering method, and a preprocessed image is obtained by combining with the linear interpolation correction projection data, and then the iterative correction is carried out on the basis of this method. The image quality is optimized by anisotropic smoothing filter during iterative processing, and the target image is obtained by multiple iterations. Experiments show that compared with the traditional segmentation and interpolation methods, this method can segment metal objects more accurately and remove metal artifacts effectively, and no new fringe artifacts. 2. Three-dimensional reconstruction of medical image: in the process of medical image reconstruction, the speed of traditional 3D surface rendering moving cube (M C) algorithm is very slow, and the organization separation is difficult. In this paper, an improved moving cube algorithm is proposed. According to the characteristics of human organs connecting, the algorithm first selects some seed elements, and then derives the whole isosurface of organs according to these seeds, thus reducing the search for useless bodies; at the same time, The normal vector and equivalent point coordinates are solved by the n-degree equipartition point method instead of the linear interpolation method, and the number of operations is reduced. The efficiency of the algorithm is improved. The three-dimensional model of artificial joint prosthesis and host bone was reconstructed. Lay the foundation for the calculation of contact area. Calculation of contact area: based on 3D reconstruction model, contact area is calculated by combining finite element contact analysis theory and meshing software. The established 3D model is imported into the grid division software H y p e r m e s h 10.0 by I G S format, and the model is meshed. In the basic theory of finite element contact analysis, the mesh nodes of the prosthesis and the femur contact part are mapped one-to-one, the number of nodes and the number of elements of the mesh are calculated, and the contact area is estimated. The relationship between contact area and loosening was discussed by calculating the contact area between prosthesis and host bone. It has strong clinical significance and value.
【學(xué)位授予單位】:河南科技大學(xué)
【學(xué)位級別】:碩士
【學(xué)位授予年份】:2015
【分類號】:R687.4;TP391.41

【參考文獻(xiàn)】

相關(guān)期刊論文 前1條

1 李鳴;;一種改進(jìn)的各向異性擴(kuò)散去噪算法[J];光電子技術(shù);2014年01期

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本文編號:2239761

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