【摘要】：目的:分析50歲以上脊柱椎體壓縮性骨折患者及健康查體者的腰椎骨密度,探討脊柱椎體壓縮性骨折與骨密度的相關(guān)性,并預(yù)測(cè)椎體壓縮性骨折的骨密度危險(xiǎn)性閾值。方法:收集來自2012年1月至2013年12月在山東省文登整骨醫(yī)院診療50歲以上脊柱椎體壓縮性骨折患者99名,以及50歲以上的查體患者208名,均進(jìn)行DR數(shù)字?jǐn)z影及使用DEXA進(jìn)行骨密度掃描,將測(cè)量所得骨密度數(shù)值輸入SPSS17.0軟件進(jìn)行統(tǒng)計(jì)學(xué)分析,應(yīng)用秩和檢驗(yàn)、t檢驗(yàn)、方差分析以及Person相關(guān)性進(jìn)行分析脊柱椎體壓縮性骨折與骨密度的相關(guān)性。結(jié)果:骨折組腰椎骨密度為0.8217?0.1744 g/cm2,對(duì)照組腰椎骨密度為1.0045?0.2076 g/cm2,骨折組骨密度與對(duì)照組骨密度差異有顯著性(p0.05)。50歲~60歲年齡段骨折組骨密度為0.8745?0.1590 g/cm2,對(duì)照組骨密度為1.0284?0.2091 g/cm2;60歲~70歲年齡段骨折組骨密度為0.7932?0.1751 g/cm2,對(duì)照組骨密度為0.9922?0.2271 g/cm2;70歲以上年齡段骨折組骨密度為0.7720?0.1604 g/cm2,對(duì)照組骨密度為0.9080?0.1881 g/cm2。這3個(gè)年齡段骨折組骨密度與對(duì)照組骨密度均有顯著性差異(p0.05)。Person相關(guān)性分析椎體壓縮性骨折與骨密度相關(guān)性pearon correlation為-2.38,Sig為0.018(p0.05)差異有顯著性。脊柱椎體壓縮性骨折的骨密度危險(xiǎn)性閾值為0.7241 g/cm2。結(jié)論:50歲以上老年人脊柱骨密度隨著年齡增大而逐步降低,脊柱椎體壓縮性骨折危險(xiǎn)性隨著骨密度的降低而增大。通過所得危險(xiǎn)性閾值可以預(yù)測(cè)脊柱椎體發(fā)生壓縮性骨折的危險(xiǎn)性。
[Abstract]:Objective: to analyze the bone mineral density (BMD) of lumbar vertebrae in patients with vertebral compression fracture over 50 years old and healthy examiner, to explore the correlation between vertebral compression fracture and bone mineral density, and to predict the risk threshold of bone mineral density (BMD) of vertebral compression fracture. Methods: from January 2012 to December 2013, 99 patients with vertebral compression fracture over 50 years old and 208 patients over 50 years old were collected from Wendeng whole Bone Hospital of Shandong Province. Dr digital photography was performed and bone mineral density was scanned by DEXA. The measured bone mineral density was input into SPSS17.0 software for statistical analysis, and rank sum test was used to test the bone mineral density (BMD). Variance analysis and Person correlation were used to analyze the correlation between vertebral compression fracture and bone mineral density. Results: the BMD of lumbar vertebrae in fracture group was 0.82170.1744 g / cm ~ 2, and that in control group was 1.0045 ~ 0.2076 g / cm ~ (-2). There was a significant difference between fracture group and control group (p0.05). The BMD of fracture group was 0.8745 ~ 0.1590 g / cm ~ (-2), and that of control group was 1.02844 ~ 0.2091 g / cm ~ (-2). Bone mineral density (BMD) was 0.7932 / 0.1751 g / cm ~ (-2) in the fracture group of 70 years old, 0.9922 ~ 0.2271 g / cm ~ (-2) in the control group, 0.7720 ~ 0.1604 g / cm ~ (-2) in the control group and 0.9080 / 0.1881 g / cm ~ (-2) in the control group. Correlation analysis of bone mineral density (BMD) between the three age group and the control group (p0. 05). The correlation between vertebral compression fracture and BMD was-2. 38 Sig = 0.018 (p0. 05). The BMD risk threshold for vertebral compression fractures is 0.7241 g / cm ~ 2. Conclusion the bone mineral density (BMD) of spinal column decreases with age and the risk of vertebral compression fracture increases with the decrease of BMD. The risk threshold can be used to predict the risk of vertebral compression fracture.
【學(xué)位授予單位】：青島大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2015
【分類號(hào)】：R683.2

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