膝骨性關節(jié)炎患者膝關節(jié)局部骨密度的差異性研究
[Abstract]:Objective to investigate the difference of bone mineral density (BMD) in different zones of knee joint in patients with knee osteoarthritis and its correlation with osteoporosis. Methods from March to July 2016, 44 patients with primary knee osteoarthritis (22 patients with left knee and 22 patients with right knee) were selected from Guangdong Provincial Hospital of Chinese Medicine, all of whom were menopausal women, aged 548.88 years (mean 68.6 鹵7.50 years). The region of interest (ROI) of knee joint was divided into 6 regions of interest (ROI 1-6) and 7 regions of interest (ROI 1-7) respectively. Dual energy X ray absorptiometry was used to measure the bone mineral density of each region of interest, and the bone mineral density of lumbar vertebrae and femoral neck. According to the measurement results, the BMD measurements in different zones were compared and the data were processed and analyzed by SPSS 16.0 software. Results 44 patients with primary knee osteoarthritis were included. The BMD of lumbar vertebrae was 0.859 鹵0.156 g/cm2 (0.592鹵 1.168 g/cm2), and that of femoral neck was 0.660 鹵0.112 g/cm2 (0.436 鹵0.087 g/cm2). Among them, 15 cases were osteoporosis (T value -2.5), 23 cases were low bone mass (-1.0 T value 2.5), and 6 cases were normal (T value -1.0), accounting for 13.6%. The BMD of ROI 1-6 in the ROI 1-6 area of the orthotopic position of the knee joint was: 0. 764 鹵0. 176 鹵0. 649 鹵0. 177 鹵0. 871 鹵0. 253 鹵0. 984 鹵0. 297V 0. 696 鹵0. 143 ~ 0. 949 鹵0. 210 respectively. The BMD of ROI 1-7 area in lateral position of knee joint was: 0. 801 鹵0. 226 鹵0. 995 鹵0. 272 鹵0. 964 鹵0. 298 9. 942 鹵0. 198 0. 796 鹵0. 157 0. 870 鹵0. 22323. 752 鹵0. 206 respectively. The bone mineral density of the area of interest in orthotopic position of knee joint was compared with that of ROI 1, ROI 2 ROI 3 ROI 3 ROI 4, and the BMD values of ROI 4 ROI 3 ROI 1 ROI 2 were significantly different among the four subdivisions (P 0.05), and the BMD values of ROI 4 ROI 3 ROI 1 ROI 2. Comparison of BMD between ROI 1 and ROI 2 ROI 3 ROI 4 in lateral area of interest of knee joint there was significant difference between BMD measurement values of roi 1 and ROI 2 ROI 3 roi 4 (P 0.05) the minimum BMD value of roi 1 BMD. ROI 4 ROI 6 was significantly different from that of ROI 5 ROI 7 (P 0.05). The BMD value of 6 is larger than that of ROI 5 / ROI 7. Conclusion most of the patients with knee osteoarthritis are complicated with osteoporosis, and the relationship between osteoarthritis and osteoporosis leads to the development of the disease. The BMD of the medial tibial plateau was higher than that of the lateral tibial plateau, and the BMD of the lateral femoral condyle was higher than that of the medial femoral condyle, and the femoral condyle and the femoral shaft were higher than those of the tibial plateau and the tibial trunk. The BMD of patella was high.
【作者單位】: 廣東省中醫(yī)院;
【基金】:廣東省中醫(yī)藥局科研項目(20172081)
【分類號】:R684.3
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