發(fā)布時間：2018-06-20 04:07

  本文選題：隨機對照試驗 + 胸腰椎骨折　； 參考：《頸腰痛雜志》2015年02期

【摘要】：目的系統(tǒng)評價植骨與否對后路短節(jié)段固定治療胸腰椎爆裂性骨折的效果。方法由兩人分別計算機檢索MEDLINE(1966-2014.7),ELSEVIER,Springerlink和Google Scholar等數(shù)據(jù)庫,收集比較后路短節(jié)段固定植骨或不植骨治療胸腰椎爆裂性骨折的隨機對照試驗進行Meta分析,并評價納入研究的方法學質量,采用Cochrane協(xié)作網(wǎng)提供的統(tǒng)計學軟件Rev Man5.3及偏倚風險評估標準進行分析。結果共納入符合標準的隨機對照試驗4篇,包含198位患者。所有納入研究的基本特征較為一致,研究發(fā)現(xiàn)后路短節(jié)段固定治療胸腰椎骨折效果滿意,植骨與非植骨在術后的臨床、影像學結果及內固定失敗等方面沒有顯著統(tǒng)計學差異。非植骨融合組在手術時間、術中出血量、避免供骨區(qū)并發(fā)癥等方面具有明顯優(yōu)勢。結論短期結果顯示同時行植骨融合對后路短節(jié)段固定治療嚴格篩選的胸腰椎爆裂性骨折(LSC評分≤6)是沒有必要的,但需要更多和更長時間的臨床驗證。
[Abstract]:Objective to evaluate the effect of bone graft on thoracolumbar burst fracture. Methods the databases of ELSEVIERN Springerlink and Google Scholar were searched by MEDLINE from June 1966-April 7, 2014.The data were collected and compared in a randomized controlled trial with or without bone graft for thoracolumbar burst fracture, and the quality of methodology was evaluated. The statistical software Rev Man5.3 provided by Cochrane Cooperative Network and the bias risk assessment criteria were used to analyze the results. Results A total of 4 randomized controlled trials including 198 patients were included. All the basic characteristics of the study were consistent. It was found that the treatment of thoracolumbar vertebrae fractures with posterior short segment fixation was satisfactory. There was no significant difference in the clinical, imaging results and internal fixation failure between bone graft and non-graft. The non-graft fusion group had obvious advantages in operation time, intraoperative bleeding volume, and avoiding complications in donor bone area. Conclusion the short term results showed that simultaneous bone graft fusion was not necessary for LSC score 鈮，

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