本文選題：脫細胞異體真皮基質(zhì) + 高位肛瘺��； 參考：《廣西醫(yī)科大學》2015年碩士論文

【摘要】：目的：觀察應用脫細胞異體真皮基質(zhì)填塞修復高位肛瘺的臨床療效,探討治療高位肛瘺的微創(chuàng)治療新方法。方法：選擇我院收治的100例高位肛瘺患者,治療組采用脫細胞異體真皮基質(zhì)填塞術,對照組采用傳統(tǒng)的肛瘺低位切開并高位掛線術,比較兩組手術時間、術后疼痛視覺模擬評分、術后疼痛持續(xù)時間、術前及術后肛門失禁程度評分、術后并發(fā)癥、創(chuàng)面愈合時間、住院時間、一期手術成功率、治愈率、復發(fā)率。結果：治療組手術時間、術后疼痛視覺模擬評分、術后疼痛持續(xù)時間、術前及術后肛門失禁程度評分、創(chuàng)面愈合時間、住院時間均低于對照組(P0.05),一期手術成功率及治愈率高于對照組(P0.05),兩組在復發(fā)率的比較、術后并發(fā)癥的比較上,差異無顯著性意義(P0.05)。結論：脫細胞異體真皮基質(zhì)填塞修復高位肛瘺的治療,在降低高位肛瘺復發(fā)率、減少術后并發(fā)癥方面與傳統(tǒng)低位切開并高位掛線術方面基本一致；在減輕患者疼痛、促進創(chuàng)面愈合、減少住院療程、降低對肛門功能及外觀的損害、提高治愈率方面具有較為顯著優(yōu)勢,可進一步在臨床中推廣應用。
[Abstract]:Objective: to observe the clinical effect of acellular allogeneic dermal matrix tamponade in the repair of high anal fistula and to explore a new method of minimally invasive treatment for high anal fistula. Methods: 100 cases of high anal fistula were treated in our hospital. The treatment group was treated with acellular allogeneic dermal matrix tamponade, and the control group was treated with the traditional low incision of anal fistula and high ligation. The time of operation was compared between the two groups. Postoperative pain visual analogue score, postoperative pain duration, preoperative and postoperative anal incontinence score, postoperative complications, wound healing time, hospitalization time, primary surgical success rate, cure rate, recurrence rate. Results: in the treatment group, the operation time, postoperative pain visual analogue score, postoperative pain duration, preoperative and postoperative anal incontinence score, wound healing time, The length of hospitalization was lower than that of control group (P 0.05). The success rate and cure rate of primary operation were higher than that of control group (P 0.05). There was no significant difference in recurrence rate and postoperative complications between the two groups. Conclusion: the treatment of acellular allogeneic dermal matrix tamponade for repairing high anal fistula can reduce the recurrence rate of high anal fistula and reduce the postoperative complications. It has obvious advantages in promoting wound healing, reducing hospitalization course, reducing damage to anal function and appearance, and increasing cure rate, which can be further popularized and applied in clinic.
【學位授予單位】：廣西醫(yī)科大學
【學位級別】：碩士
【學位授予年份】：2015
【分類號】：R657.16

【參考文獻】

相關期刊論文 前10條

1 江厚象 ,王東 ,潘凱 ,夏利剛 ,陳小春 ,楊曉東 ,鐘克力 ,王紅艷;分期手術并用纖維蛋白膠治療復雜肛瘺的應用體會(附14例臨床報告)[J];大腸肛門病外科雜志;2004年01期

2 田穎;于洪順;秦澎湃;王彥芳;田磊;葛強;劉智永;;脫細胞真皮基質(zhì)治療伴高位盲瘺的復雜性肛瘺療效觀察(附39例報告)[J];結直腸肛門外科;2012年03期

3 仲貴香;;隧道式拖線術治療復雜性肛瘺50例[J];陜西中醫(yī);2012年03期

4 李英;杜志剛;;脫細胞異體真皮基質(zhì)口腔黏膜補片治療口腔黏膜缺損:隨機對照[J];中國組織工程研究與臨床康復;2008年19期

5 劉飛德;李基業(yè);姚勝;王世斌;朱瑛梅;;脫細胞真皮基質(zhì)修補腹股溝疝[J];中國組織工程研究與臨床康復;2011年25期

6 劉坡;祁少海;舒斌;謝舉臨;徐盈斌;劉旭盛;;異體脫細胞真皮基質(zhì)作為組織工程皮膚真皮支架的可行性[J];中國組織工程研究;2012年21期

7 胡燕平;郭雋;宋捷;馬銳;王欣;王雪;;脫細胞異體真皮基質(zhì)的遺傳毒性研究[J];中國醫(yī)療器械信息;2012年03期

8 王振軍;宋維亮;鄭毅;彭亞平;楊新慶;趙博;;AEM治療肛瘺30例[J];中國臨床醫(yī)生;2008年08期

9 陳朝文;;復雜肛瘺的治療[J];中國普外基礎與臨床雜志;2010年02期

10 譚嗣偉;梁存河;陳志雨;楊建林;張帆;;脫細胞異體真皮基質(zhì)材料治療復雜肛瘺52例[J];中國微創(chuàng)外科雜志;2012年03期

，

本文編號：1999119