本文選題：脂肪顆粒 + 自體脂肪　； 參考：《華北理工大學(xué)》2015年碩士論文

【摘要】：目的1研究自體脂肪顆粒隆乳術(shù)術(shù)中提純脂肪顆粒的不同方法(離心法和靜置法)對(duì)術(shù)后脂肪移植成活率的影響;2采用同一方法(離心法)脂肪顆粒多次少量注射與大量單次注射對(duì)術(shù)后脂肪移植成活率的比較。3比較三種方法術(shù)后移植脂肪成活率在腺體層和肌層是否不同。方法實(shí)驗(yàn)分為A、B、C三組,A組7例13側(cè),B組8例14側(cè),C組6例12側(cè),每組手術(shù)方法相同,脂肪抽取方法相同,注射層次大體相同,A組和B組僅脂肪提純方法不同,A組將抽取后的脂肪采用靜止法提純,B組采用低速離心法提純;B組和C組提純方法相同僅注射次數(shù)和注射量不同,B組采用單次大劑量注射提純后的脂肪顆粒,C組分三次小劑量注射,每次注射時(shí)間間隔三個(gè)月。每位患者就診后首先預(yù)測(cè)乳房所需填充脂肪量和供區(qū)脂肪厚度,術(shù)前常規(guī)檢查后,術(shù)前當(dāng)日留取影像資料方便術(shù)后效果對(duì)比,并B超測(cè)量乳房各層厚度(數(shù)值可精確至0.01cm),術(shù)后七天、術(shù)后一月、術(shù)后三月進(jìn)行回訪調(diào)查留取影像資料和B超測(cè)量數(shù)據(jù),術(shù)后三個(gè)月后乳房形態(tài)基本不會(huì)再變化,計(jì)算出術(shù)后七天、術(shù)后一月、術(shù)后三月移植脂肪的成活率,每組數(shù)據(jù)比較各時(shí)間段移植脂肪的成活率,A組和B組成活率的比較可以反應(yīng)哪種脂肪提純方法脂肪成活率較高,B組和C組成活率的比較可以反應(yīng)單次大量注射和少量多次注射的術(shù)后效果。結(jié)果A組靜置法大量單次注射隆乳術(shù)術(shù)后測(cè)得:腺體層術(shù)后1個(gè)月平均厚度為0.38±0.06cm(成活率46.12±4.14%),術(shù)后3個(gè)月平均厚度為0.30±0.04cm(成活率41.13±2.99%);肌層層術(shù)后1個(gè)月平均厚度為0.30±0.04cm(成活率47.11±5.56%),術(shù)后3個(gè)月平均厚度為0.27±0.03cm(成活率43.52±5.18%);B組離心法大量單次注射隆乳術(shù)術(shù)后測(cè)得:腺體層術(shù)后1個(gè)月平均厚度為0.48±0.12cm(成活率53.09±2.13%),術(shù)后3個(gè)月平均厚度為0.44±0.14cm(成活率48.52±4.21%);肌層術(shù)后1個(gè)月平均厚度為0.41±0.11cm(成活率54.67±3.30%),術(shù)后3個(gè)月平均厚度為0.40±0.10cm(成活率52.82±2.80%)。C組離心法三次少量注射隆乳術(shù)病例測(cè)得數(shù)據(jù):第一次術(shù)后三個(gè)月腺體層成活率為51.25±1.39%,肌層成活率為55.25±3.32%;第二次術(shù)后三個(gè)月腺體層成活率為50.76±2.16%,肌層成活率為54.95±3.12%;第三次術(shù)后三個(gè)月腺體層成活率為49.30±3.19%,肌層成活率為56.42±3.78%。將三次注射累計(jì)注射厚度和成活厚度來(lái)計(jì)算,腺體層成活率為50.39±1.36%,肌層成活率為55.54±2.59%。結(jié)論1提純方法比較,低速離心法要比靜置法術(shù)后成活率高;離心法比較,少量多次注射比單次大量注射成活率高。2腺體層和肌層成活率比較,靜置法單次大量注射兩個(gè)層次成活率沒有明顯差別,離心法少量多次和大量單次注射肌層成活率均高于腺體層。
[Abstract]:Objective 1 to study the effect of different methods (centrifugal method and static method) on the survival rate of fat transplantation during augmentation mammoplasty with autologous fat granules. Comparison of survival rate of fat transplantation between single injection and mass injection. 3 comparison of survival rate of fat graft in glandular layer and muscle layer by three methods. Methods the experiment was divided into three groups: group A, group B, group B: 8 cases, group B, group C, 6 cases, 12 sides. Each group had the same operation method and the same method of fat extraction. The level of injection is roughly the same as that of group A and group B only the methods of fat purification are different. Group A uses static method to purify the extracted fat. Group B is purified by low speed centrifugation. Group B and group C are purified with the same methods only the number of times of injection and the amount of injection are not the same. Group B was injected with three small doses of single large dose injection of fat granule C after purification. The time interval for each injection was three months. Each patient first predicted the amount of fat needed to fill the breast and the thickness of the donor fat. After routine preoperative examination, the images were taken on the same day to facilitate the comparison of postoperative results. The thickness of each layer of breast was measured by B-ultrasound (the value can be accurate to 0.01 cm ~ (-1). Seven days after operation, one month after operation, and three months after operation, the imaging data and the data measured by B-mode ultrasound were collected. After three months of operation, the shape of the breast was basically no longer changed. Calculate the survival rate of fat grafts seven days, one month and three months after operation, The comparison of survival rate of group A and group B can reflect which method of fat purification is higher. The comparison of survival rate of group B and group C can reflect the single mass injection and the comparison of survival rate of group C and group B can reflect the survival rate of fat grafts in each time period. The postoperative effect of a small amount of multiple injections. Results in group A, the average thickness of glandular layer was 0.38 鹵0.06 cm (survival rate 46.12 鹵4.14 cm) and 0.30 鹵0.04 cm (survival rate 41.13 鹵2.99 cm) 1 month after operation and 0.30 鹵0.04 cm (survival rate 41.13 鹵2.99 cm) in group A. The average thickness was 0.27 鹵0.03 cm (survival rate 43.52 鹵5.18) in group B: the mean thickness of glandular layer was 0.48 鹵0.12 cm (survival rate 53.09 鹵2.13 cm) 1 month after operation, and the mean thickness of muscle layer was 0.44 鹵0.14 cm (survival rate 48.52 鹵4.21 cm) in 3 months after operation. The mean thickness was 0.41 鹵0.11 cm (survival rate 54.67 鹵3.30 cm) and 0.40 鹵0.10 cm (survival rate 52.82 鹵2.80 cm) in group C: the survival rate of glandular layer was 51.25 鹵1.39 in the first three months after operation, and the survival rate of muscular layer was 51.25 鹵1.39 in the first three months after operation. The survival rate of glandular layer was 55.25 鹵3.322.The survival rate of glandular layer and muscular layer was 50.76 鹵2.16and 54.95 鹵3.12respectively, and the survival rate of glandular layer was 49.30 鹵3.19 and the survival rate of muscular layer was 56.42 鹵3.78 three months after the third operation. The survival rate of glandular layer and muscle layer was 50.39 鹵1.36 and 55.54 鹵2.59 respectively. Conclusion (1) the survival rate of low speed centrifugation is higher than that of static spell, and the survival rate of small amount of multiple injection is higher than that of single mass injection of 2. 2% higher than that of muscle layer. There was no significant difference in survival rate between the two levels of single mass injection by static method. The survival rate of myometrium injected by centrifugal method was higher than that of glandular layer.
【學(xué)位授予單位】：華北理工大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2015
【分類號(hào)】：R622

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本文編號(hào)：1937245