本文選題：術(shù)后認知功能障礙 + 異丙酚　； 參考：《中國醫(yī)科大學學報》2016年09期

【摘要】：目的比較七氟烷與異丙酚對老年患者局部腦氧飽和度及術(shù)后早期認知功能的影響。方法選擇于胸腔鏡下行肺癌根治術(shù)的患者60例,男女不限,年齡65~75歲,美國麻醉醫(yī)師協(xié)會(ASA)分級Ⅰ~Ⅱ級,采用隨機數(shù)字表法將患者隨機分為2組:七氟烷組(S組)與異丙酚組(P組)。2組患者均于入室后持續(xù)監(jiān)測局部腦氧飽和度直至拔管,分別于術(shù)前1 d及術(shù)后7 d進行神經(jīng)心理學測試,評價患者認知功能,根據(jù)Z計分法計算術(shù)后認知功能障礙發(fā)生率。結(jié)果 2組患者單肺通氣期間均發(fā)生局部腦氧飽和度降低。2組患者術(shù)后認知功能障礙發(fā)生率無統(tǒng)計學差異,但與P組比較,術(shù)后7 d S組簡易精神狀態(tài)評價量表(MMSE)評分、數(shù)字廣度測試(順背和逆背)評分、詞匯流暢性測試評分降低(P0.05)。結(jié)論七氟烷復(fù)合麻醉與異丙酚復(fù)合麻醉對單肺通氣期間局部腦氧飽和度的影響無統(tǒng)計學差異;S組術(shù)后7 d認知功能較P組有所降低(P0.05)。
[Abstract]:Objective to compare the effects of sevoflurane and propofol on regional cerebral oxygen saturation and early postoperative cognitive function in elderly patients. Methods A total of 60 patients (male and female, 6575 years old) undergoing thoracoscopic radical resection of lung cancer were enrolled in this study. The American Association of Anesthesiologists (ASA) was classified as grade 鈪，

本文編號：1918452