正常人群256CT下頭皮灌注參數(shù)值范圍的定量研究—智能優(yōu)化算法在大面積顱骨修補(bǔ)術(shù)后皮瓣評估的研究及轉(zhuǎn)化應(yīng)用
發(fā)布時間:2018-05-15 03:15
本文選題:CT灌注 + 頭皮; 參考:《昆明醫(yī)科大學(xué)》2015年碩士論文
【摘要】:目的:測定正常人群256CT下頭皮灌注參數(shù)值[組織血容量(TBV)、組織血容量(TBF)、達(dá)峰時間(TTP)]范圍。材料與方法:選取31例正常人在256 CT下行頭皮灌注檢查,經(jīng)肘靜脈注射非離子型對比劑碘海醇50 ml,延遲8s后,行灌注檢查。用Functional灌注軟件包行灌注圖像后處理,由兩名有經(jīng)驗神經(jīng)影像診斷醫(yī)師對圖像進(jìn)行分析,測定額部、顳部、枕部灌注參數(shù)值,計算出31例患者頭皮灌注參數(shù)的平均值及標(biāo)準(zhǔn)差,進(jìn)一步通過SPSS 17.0進(jìn)行統(tǒng)計分析得出正常人群頭皮灌注正常值范圍,并對不同部位灌注值做統(tǒng)計學(xué)比較。結(jié)果:額部正常值范圍為TBF:(25.18-85.66) ml/(100g.min)、TBV:(13.97-55.99) ml/100g、TTP:(16.38-37.82) S;顳部:TBF:(18.39-76.87) ml/(100g.min)、 TBV:(13.42-64.58) ml/100g、TTP (18.79-35.81) S;枕部:TBF:(9.00-37.70) ml/(100g.min)、TBV (10.28-31.96) ml/100g、TTP (26.85-42.85)S。對額部、顳部灌注參數(shù)平均值(TBV、TBF、TTP)做兩獨立樣本T檢驗差異無統(tǒng)計學(xué)意義(P0.05),分別對額部與枕部、顳部與枕部的頭皮灌注數(shù)值做兩獨立樣本T檢驗,額部、顳部灌注值大于枕部,差異有統(tǒng)計學(xué)意義(P0.05)。結(jié)論:256CT下測量頭皮灌注值為頭皮血液動力學(xué)的測定提供了一種新的方法,256CT下頭皮灌注值范圍可以測定頭皮血液動力學(xué)情況,為進(jìn)一步解決大面積顱骨修補(bǔ)術(shù)后鈦網(wǎng)外露奠定了基礎(chǔ)。
[Abstract]:Objective: to determine the parameters of scalp perfusion parameters (tissue blood volume (TBV), tissue blood volume (TBF) and peak time (TTP)) under 256CT in normal population. Materials and methods: 31 normal people were examined under 256 CT scalp perfusion, and 50 ml of non ionic contrast agent iodiol was injected by the elbow vein, after delayed 8s, perfusion examination was performed with Functional perfusion. The images were analyzed by two experienced neuroimaging diagnostics, and the parameters of the frontal, temporal and occipital perfusion parameters were measured by two experienced neuroimaging diagnostics. The average value and standard deviation of the scalp perfusion parameters in 31 patients were calculated. The normal range of the normal scalp perfusion in normal population was analyzed by SPSS 17. Results: the range of normal value is TBF: (25.18-85.66) ml/ (100g.min), TBV: (13.97-55.99) ml/100g, TTP: (16.38-37.82) S, and temporal: TBF: (18.39-76.87). /100g, TTP (26.85-42.85) S. (TBV, TBF, TTP) of the frontal and temporal perfusion parameters (TBV, TBF, TTP) did not have statistical significance (P0.05) for two independent samples. The value of the scalp perfusion in the frontal and occipital areas, the temporal and occipital scalp was examined by T, and the value of the frontal and temporal perfusion was greater than that of the occipital region. The difference was statistically significant (P0.05). Conclusion: 256C The measurement of scalp perfusion under T provides a new method for the determination of the hemodynamics of scalp. The range of scalp perfusion value under 256CT can be used to determine the hemodynamics of the scalp, which lays a foundation for further solving the titanium mesh exposure after large area cranioplasty.
【學(xué)位授予單位】:昆明醫(yī)科大學(xué)
【學(xué)位級別】:碩士
【學(xué)位授予年份】:2015
【分類號】:R651.1
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