本文選題：急性闌尾炎 + 中性粒細(xì)胞與淋巴細(xì)胞比值�。� 參考：《延邊大學(xué)》2016年碩士論文

【摘要】：目的探討中性粒細(xì)胞與淋巴細(xì)胞比值(neutrophil to lymphocyte ratio, NLR)、血小板與淋巴細(xì)胞比值(platelet to lymphocyte ratio, PLR)與成人急性闌尾炎(acute appendicitis, AA)I臨床病理分型的關(guān)系和臨床意義。方法收集2012年1月到2015年8月間在我院普外科行闌尾切除并術(shù)后病理證實(shí)為AA的成人患者353例及同期健康成人體檢者50例,根據(jù)臨床病理分型將AA患者分為急性單純性闌尾炎組(A1組)、急性蜂窩織性闌尾炎組(A2組)、急性壞疽性闌尾炎組(A3組)；健康成人體檢者(B組),采集各組患者術(shù)前血常規(guī)各項(xiàng)指標(biāo),計(jì)算NLR和PLR比值,比較分析各組NLR和PLR與AA病理分型的關(guān)系。結(jié)果1.A組患者NLR和PLR明顯高于B組(P0.0001)；A組內(nèi)NLR及PLR的數(shù)據(jù)差異有統(tǒng)計(jì)學(xué)意義(P0.0001)；A1-A3組間NLR差異有統(tǒng)計(jì)學(xué)意義(P0.0001)；PLR在A1和A3組差異有統(tǒng)計(jì)學(xué)意義(P0.0001),A1和A2組、A2和A3組差異無(wú)統(tǒng)計(jì)學(xué)意義(均P0.017)。2.A1-A3組NLR的ROC曲線下面積各為0.707,0.952和0.972；PLR的ROC曲線下面積各為0.737,0.791和0.829；與對(duì)照組比較均有顯著性差異(均P0.0001)。3.A1-A3各組NLR的ROC曲線cut-off值各為1.63、4.97和5.89,靈敏度52.08%、89.51%、96.88%,特異性68.55%、98%、98%；(均P0.0001)。A1-A3各組PLR的ROC曲線cut-off值各為81.63、131.78和184.54,靈敏度41.35%、53.23%、60.42%,特異性均100%；(均P0.00015)。結(jié)論術(shù)前NLR和PLR可作為AA臨床病理分型的指標(biāo)；NLR較PLR對(duì)AA具有更好的診斷敏感性。
[Abstract]:Objective to investigate the relationship between neutrophil to lymphocyte ratio, NLRN, platelet-lymphocyte ratio to lymphocyte ratio, PLR) and acute appendicitis (AA)I) in adults with acute appendicitis (AA)I) and its clinical significance. Methods from January 2012 to August 2015, 353 adult patients underwent appendectomy and confirmed AA by pathology in our hospital and 50 healthy adults were examined in the same period. According to the clinicopathological classification, AA patients were divided into acute simple appendicitis group A 1 group, acute cellulocytic appendicitis group A 2 group, acute gangrene appendicitis group A 3 group, healthy adults group B group, blood routine examination of each group before operation. The ratio of NLR and PLR was calculated, and the relationship between NLR and PLR and the pathological classification of AA was compared and analyzed. Results 1. NLR and PLR in group A were significantly higher than those in group B (P 0.0001A). There was significant difference in NLR and PLR between group A and group A (P 0.0001A 1-A 3). There was significant difference between group A and group A (P 0.0001). There was no significant difference between group A (P 0.0001A 1) and group A (A 2) and group A 3 (P 0.0001A 3). (the area under ROC curve of NLR in P0.017).2.A1-A3 group was 0.7070.952 and the area under ROC curve of 0.972L PLR was 0.7370.791 and 0.829 respectively, and there was significant difference compared with control group (cut-off value of ROC curve of NLR in all P0.0001).3.A1-A3 groups were 1.634.97 and 5.89, sensitivity 52.0889.51d) and specificity were 96.888.The area under ROC curve of NLR in P0.017).2.A1-A3 group was 0.7070.9952 and 0.972plr was 0.737-0.791 and 0.829, respectively, and the cut-off value of ROC curve of P0.0001).3.A1-A3 group was 1.634.97 and 5.89 respectively. The ROC curve cut-off values of PLR in all P0.0001).A1-A3 groups were 81.63131.78 and 184.54, respectively. The sensitivity of 41.35 and 53.23was 60.42, and the specificity was 100 (P 0.00015). Conclusion preoperative NLR and PLR are more sensitive than PLR in the diagnosis of AA.
【學(xué)位授予單位】：延邊大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2016
【分類號(hào)】：R656.8

【相似文獻(xiàn)】

相關(guān)期刊論文 前10條

1 楊閏平,王維清;吸煙與急性闌尾炎(1)[J];國(guó)外醫(yī)學(xué)(醫(yī)學(xué)地理分冊(cè));2000年04期

2 李雄,朱鳳江,，

本文編號(hào)：1881899