本文選題：克羅恩病 + 預(yù)后營養(yǎng)指數(shù)　； 參考：《浙江大學(xué)》2015年碩士論文

【摘要】：目的：探討預(yù)后營養(yǎng)指數(shù)(PNI)對克羅恩病患者術(shù)后近期并發(fā)癥的預(yù)測作用。 方法：本研究收集2012年1月至2014年12月的73例行腸段切除的克羅恩病患者的臨床資料。男性46例,女性27例,平均年齡36.14歲。根據(jù)患者術(shù)前外周血白蛋白和淋巴細胞計數(shù),采用公式10×白蛋白濃度(g/dl)+0.005×淋巴細胞計數(shù)(/mm3)計算PNI值。將患者分為兩組：一組PNI40(30例),另一組PNI40(43例),比較兩組間臨床和實驗室各項指標差異,并采用logistic回歸分析并發(fā)癥相關(guān)危險因素。 結(jié)果：PNI40和PNI40兩組間BMI(17.9±2.4vs.19.2±2.25,p0.05)差異有統(tǒng)計學(xué)意義。PNI40組術(shù)后總體并發(fā)癥和感染性并發(fā)癥例數(shù)分別是15例(50.0%)和14例(46.7%)；PNI≥40組分別是10例(23.3%)和7例(16.3%),差異有統(tǒng)計學(xué)意義p0.05)。術(shù)后住院天數(shù)兩組間差異無統(tǒng)計學(xué)意義60=0.138)。單因素分析顯示BMI18.5,穿透型病變,傳統(tǒng)開放手術(shù)和PNI40與總體并發(fā)癥和感染性并發(fā)癥相關(guān)。而多因素分析提示只有PNI40是感染性并發(fā)癥的獨立預(yù)后指標(OR：3.846,95%置信區(qū)間[1.145-12.821])。 結(jié)論：術(shù)前預(yù)后營養(yǎng)指數(shù)(PNI)是克羅恩病患者術(shù)后近期感染性并發(fā)癥的有效預(yù)測指標。
[Abstract]:Objective: to investigate the prognostic effect of PNII on postoperative complications in patients with Crohn's disease. Methods: the clinical data of 73 patients with Crohn's disease were collected from January 2012 to December 2014. There were 46 males and 27 females with an average age of 36.14 years. According to the preoperative peripheral blood albumin and lymphocyte count, the PNI value was calculated by the formula of 10 脳 albumin concentration (g / dl) 0.005 脳 lymphocyte count (r / mm ~ (3)). The patients were divided into two groups: one group of PNI40(30 cases and the other group of PNI40(43 cases. The differences of clinical and laboratory indexes between the two groups were compared, and the risk factors of complications were analyzed by logistic regression analysis. Results there was a significant difference in BMI(17.9 鹵2.4vs.19.2 鹵2.25 2.4vs.19.2 between the two groups. The total postoperative complications and infectious complications in the PNI40 group were 15 cases (50.0%) and 14 cases (46.7%) were 10 cases (23. 3%) and 7 cases (16. 3%), respectively. The difference was statistically significant (p0 05). There was no significant difference in postoperative hospitalization days between the two groups. Univariate analysis showed that BMI 18. 5, penetrating lesions, traditional open surgery and PNI40 were associated with overall and infectious complications. Multivariate analysis showed that only PNI40 was an independent prognostic marker of infectious complications with OR: 3.846 / 95% confidence interval [1.145-12.821]. Conclusion: preoperative prognostic nutrition index (PNII) is an effective predictor of postoperative infectious complications in patients with Crohn's disease.
【學(xué)位授予單位】：浙江大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2015
【分類號】：R656.9

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相關(guān)期刊論文 前1條

1 左蘆根;李毅;王宏剛;朱維銘;曹磊;張偉;龔劍峰;李寧;黎介壽;;術(shù)前營養(yǎng)不良對克羅恩病病人術(shù)后并發(fā)癥和復(fù)發(fā)的影響[J];腸外與腸內(nèi)營養(yǎng);2012年03期

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