本文選題：動脈瘤 + 術后腦梗死�。� 參考：《廣西醫(yī)科大學》2017年碩士論文

【摘要】：目的:探討顱內動脈瘤夾閉術后發(fā)生腦梗死的相關危險因素。方法:回顧性分析2012年1月-2016年6月期間在廣西醫(yī)科大學第一附屬醫(yī)院神經外科行顱內動脈瘤夾閉術的143例顱內動脈瘤患者的臨床資料,分別對143例患者的年齡、性別、吸煙史、糖尿病史、高血壓病史、入院時的WFNS分級、Hunt-Hess分級、改良Fisher分級、手術時機、腦血管痙攣、術中臨時阻斷載瘤動脈、術中動脈瘤破裂、瘤體大小、位置等14個指標進行單因素分析,理論頻數小于5者使用Fisher確切概率法,篩選出有顯著性的單因素,再進行多因素Logistic回歸模型分析,得出顱內動脈瘤開顱夾閉術后腦梗死的危險因素,并對結果進行討論和分析,P0.05被認為差異有統(tǒng)計學意義。結果:單因素統(tǒng)計學分析顱內瘤夾閉術后發(fā)生腦梗死的危險因素包括患者的H-H等級評分、腦血管痙攣、術中破裂;將單因素分析差異有顯著性的因素進行Logistic回歸模型的多因素分析,結果顯示:腦血管痙攣及術中動脈瘤破裂是顱內動脈瘤夾閉術后發(fā)生腦梗死的危險因素。結論:腦血管痙攣和術中動脈瘤破裂是顱內動脈瘤夾閉術后發(fā)生腦梗死的獨立危險因素,兩者均可能增加顱內動脈瘤夾閉術后腦梗死的發(fā)生風險。
[Abstract]:Objective: to investigate the risk factors of cerebral infarction after intracranial aneurysm clipping. Methods: the clinical data of 143 patients undergoing intracranial aneurysm clipping from January 2012 to June 2016 in the Neurosurgery Department of the first affiliated Hospital of Guangxi Medical University were retrospectively analyzed. History of smoking, history of diabetes, history of hypertension, WFNS grade on admission and Hunt-Hess grade, modified Fisher grade, timing of operation, cerebral vasospasm, temporary occlusion of aneurysm during operation, rupture of aneurysm during operation, tumor size, The 14 indexes such as position were analyzed by single factor analysis. Those whose theoretical frequency was less than 5 used Fisher exact probability method to screen out the significant single factor, and then carried out the multivariate Logistic regression model analysis. The risk factors of cerebral infarction after intracranial aneurysm clipping were obtained and the results were discussed and analyzed (P0.05). Results: univariate statistical analysis of the risk factors of cerebral infarction after intracranial tumor clipping included H-H grade score, cerebral vasospasm, intraoperative rupture. The multivariate analysis of univariate analysis showed that cerebral vasospasm and aneurysm rupture during operation were the risk factors of cerebral infarction after intracranial aneurysm clipping. Conclusion: cerebral vasospasm and aneurysm rupture during operation are independent risk factors of cerebral infarction after intracranial aneurysm clipping, both of which may increase the risk of cerebral infarction after intracranial aneurysm clipping.
【學位授予單位】：廣西醫(yī)科大學
【學位級別】：碩士
【學位授予年份】：2017
【分類號】：R651.12

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