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退行性腰椎管狹窄癥與腰椎矢狀位曲度異常相關(guān)性研究

發(fā)布時(shí)間:2018-04-26 08:01

  本文選題:退行性腰椎管狹窄癥 + 腰椎曲度; 參考:《鄭州大學(xué)》2017年碩士論文


【摘要】:目的研究退行性腰椎管狹窄癥腰椎曲度異常與狹窄程度的相關(guān)性,以探討腰椎管狹窄病變的發(fā)展規(guī)律,為了解病變程度、制定治療方案、判斷預(yù)后以及評價(jià)療效提供理論依據(jù)。方法回顧性分析2014年1月至2016年12月于鄭州大學(xué)第一附屬醫(yī)院骨科收治的腰椎管狹窄患者資料,根據(jù)納入標(biāo)準(zhǔn)和排除標(biāo)準(zhǔn),選取患者59例作為觀察組(A組),并選取55例健康體檢者作為正常對照組(B組)。兩組根據(jù)性別各分為男女亞組。所有對象均接受腰椎MRI檢查,在MRI矢狀像上以腰椎前凸中心法(CLL)測量腰椎曲度。并對A組在MRI軸位像上測量硬膜囊面積(DAC)、骨性椎管面積(BAC)、硬膜囊面積/骨性椎管面積(DAC/BAC)。AB兩組CLL角比較采用獨(dú)立樣本t檢驗(yàn)。A組中CLL角與DAC、BAC、DAC/BAC關(guān)系應(yīng)用Pearson相關(guān)性分析。P0.05為差異有統(tǒng)計(jì)學(xué)意義?結(jié)果1.(1)A組男女CLL平均角度分別為9.26±3.18;10.56±3.21。B組男女CLL平均角度分別為12.59±1.84;22.32±3.19。?A組與B組男女CLL角度相比均具有差異有統(tǒng)計(jì)學(xué)意義(男、女t值分別為3.042,5.784;p值分別為0.004,0.000)。2.(1)A組男女DAC平均面積分別為85.34±20.02,78.96±11.71;男女BAC平均面積分別為220.42±18.76,220.90±10.30;男女DAC/BAC平均比值分別為0.387±0.084,0.357±0.048。(2)A組男女CLL角與DAC均具有顯著相關(guān)性(男女r值分別為0.788,0.841;p值均為0.000)。A組男女CLL角與DAC/BAC均具有顯著相關(guān)性(男女r值分別為0.754,0.850;p值均為0.000)。A組男女CLL角與BAC均無顯著相關(guān)性(男女r值分別為0.319,0.245;p值分別為0.075;0.218)。結(jié)論1.退行性腰椎管狹窄癥患者較健康人腰椎曲度變直。2.腰椎管狹窄程度與腰椎曲度異常有顯著正相關(guān)性。
[Abstract]:Objective to study the relationship between the degree of lumbar curvature and the degree of degenerative lumbar spinal stenosis in order to explore the development rule of lumbar spinal stenosis, and to provide theoretical basis for understanding the degree of disease, formulating treatment plan, judging prognosis and evaluating curative effect. Methods from January 2014 to December 2016, the data of patients with lumbar spinal stenosis treated in the Department of Orthopaedics of the first affiliated Hospital of Zhengzhou University were retrospectively analyzed. 59 patients were selected as observation group A and 55 healthy persons as normal control group. The two groups were divided into male and female subgroups according to gender. All subjects underwent lumbar MRI examination and lumbar curvature was measured on MRI sagittal images. In group A, the area of dural sac, the area of bony spinal canal and the area of dural sac / bony spinal canal were measured on the axial images of MRI. The CLL angle of group A was compared with that of group A by using independent sample t test. Pearson correlation analysis was used to analyze the relationship between CLL angle and DACBACDAC- BAC in group A. P0.05 for the difference was statistically significant? Results 1. The average angle of CLL in group A was 9.26 鹵3.18 鹵10.56 鹵3.21.B, respectively. The mean angle of CLL in group A was 12.59 鹵1.84 鹵3.19.0.32 鹵3.19.A, respectively. There was significant difference in CLL angle between group A and group B (male, male). The mean area of DAC in group A was 85.34 鹵20.02 鹵78.96 鹵11.71, the mean area of BAC in men and women was 220.42 鹵18.76220.90 鹵10.30, and the average ratio of DAC/BAC was 0.387 鹵0.0840.357 鹵0.048.2P in group A (r = 0.7880.841p for males and females, respectively). There was significant correlation between CLL angle and DAC/BAC in group A (r = 0.7540.50p). There was no significant correlation between CLL angle and BAC in group A (r = 0.3190.245p = 0.0750.218p, respectively). Conclusion 1. The lumbar curvature of degenerative lumbar spinal stenosis patients was straightened. 2. There was a significant positive correlation between lumbar spinal stenosis and abnormal lumbar curvature.
【學(xué)位授予單位】:鄭州大學(xué)
【學(xué)位級別】:碩士
【學(xué)位授予年份】:2017
【分類號】:R681.5

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