本文選題：地佐辛　切入點(diǎn)：芬太尼　出處：《重慶醫(yī)學(xué)》2017年07期

【摘要】：目的比較地佐辛與芬太尼分別復(fù)合丙泊酚行靜脈全身麻醉(全麻)時(shí)的安全窗。方法選擇擬在靜脈全身麻醉下行無(wú)痛宮腔鏡手術(shù)的患者80例,采用隨機(jī)數(shù)字表法將患者分為丙泊酚復(fù)合芬太尼組(PF組)、丙泊酚復(fù)合地佐辛組(PD組),每組40例。測(cè)定每組抑制體動(dòng)及抑制呼吸的半數(shù)有效濃度(EC50),同組內(nèi)兩EC50間的差值視為安全窗,統(tǒng)計(jì)比較兩組安全窗的寬度,并記錄患者術(shù)前基礎(chǔ)(T0)、血藥濃度達(dá)穩(wěn)定(T1)、切皮(T2)、切皮后5 min(T3)、術(shù)畢拔管(T4)時(shí)的平均動(dòng)脈壓(MAP)、心率(HR)。結(jié)果 PD組安全窗寬度明顯高于PF組(P0.05)。PD組T1~3時(shí)刻的MAP及HR明顯高于PF組(P0.05)。結(jié)論地佐辛復(fù)合丙泊酚行靜脈全身麻醉時(shí),在抑制呼吸和體動(dòng)反應(yīng)間的安全窗更寬,安全性優(yōu)于芬太尼。
[Abstract]:Objective to compare the safety windows of dizosin and fentanyl combined with propofol during intravenous general anesthesia.Methods Eighty patients undergoing painless hysteroscopy under intravenous general anesthesia were randomly divided into propofol combined with fentanyl group (PF group) and propofol combined with dizosin group (PD group) with 40 cases in each group.EC50 was measured in each group. The difference between the two EC50 in the same group was regarded as a safe window, and the width of the safe window was statistically compared between the two groups.The mean arterial pressure (MAPP) and heart rate (HRT) were recorded in patients with T0, T1, T2, T3, T4 after extubation.Results the width of safe window in PD group was significantly higher than that in PF group (P 0.05). The MAP and HR of PD group were significantly higher than that of PF group (P 0.05).Conclusion the safety window of dizosin combined with propofol is wider than that of fentanyl during general intravenous anesthesia.
【作者單位】： 南方醫(yī)科大學(xué)附屬小欖人民醫(yī)院麻醉科;
【基金】：廣東省中山市科技計(jì)劃項(xiàng)目(2014A1FC117)
【分類號(hào)】：R614.24

【相似文獻(xiàn)】

相關(guān)期刊論文 前1條

1 王海燕;;精神病醫(yī)院的革命性創(chuàng)舉——“防撞式安全窗”誕生實(shí)錄[J];中國(guó)醫(yī)院建筑與裝備;2009年04期

相關(guān)重要報(bào)紙文章 前1條

1 本報(bào)記者 聞洪 劉慶斌;安防比招 “國(guó)強(qiáng)”顯秀[N];中國(guó)房地產(chǎn)報(bào);2004年

，

本文編號(hào)：1717698