發(fā)布時間：2018-03-31 23:22

  本文選題：動脈粥樣硬化性狹窄　切入點：腦動脈閉塞　出處：《中國腦血管病雜志》2017年05期

【摘要】：目的 探討氙CT腦血流灌注成像技術(shù)在腦血運重建術(shù)前及療效評估中的作用。方法 回顧性分析15例癥狀性前循環(huán)供血動脈粥樣硬化性狹窄或閉塞患者的臨床資料,其中行血管內(nèi)支架置入術(shù)8例、頸內(nèi)動脈內(nèi)膜切除術(shù)1例和顳淺動脈-大腦中動脈旁路移植術(shù)6例,對比術(shù)前與術(shù)后2周內(nèi)氙CT檢測的局部腦血流量(r CBF)及術(shù)后6個月改良Rankin量表(mRS)評分。結(jié)果 (1)12例術(shù)前靶血管遠(yuǎn)端血流灌注異�；颊咂骄鵵 CBF值為(30±10)ml/(100 g·min),術(shù)后為(32±14)ml/(100 g·min),與術(shù)前比較差異有統(tǒng)計學(xué)意義(P=0.044);3例術(shù)前靶血管遠(yuǎn)端血流灌注正�；颊咂骄鵵 CBF值為(48±6)ml/(100 g·min),術(shù)后平均r CBF值為(50±7)ml/(100 g·min),與術(shù)前比較差異無統(tǒng)計學(xué)意義(P0.05)。(2)術(shù)后mRS評分改善8例,穩(wěn)定7例。15例患者術(shù)后mRS評分為[1(0,3)]分,與術(shù)前[3(1,3)]分比較,差異有統(tǒng)計學(xué)意義(P0.05)。隨訪期間無一例新發(fā)神經(jīng)功能障礙。結(jié)論 血運重建術(shù)可改善術(shù)前存在血流動力學(xué)障礙的癥狀性前循環(huán)供血動脈狹窄或閉塞患者的靶血管遠(yuǎn)端局部腦血流灌注及神經(jīng)功能缺損癥狀,而術(shù)前氙CT腦血流灌注成像灌注異�？赡茌^灌注正�；颊攉@益更多。
[Abstract]:Objective to investigate the role of xenon CT perfusion imaging before and after cerebral revascularization. Methods the clinical data of 15 patients with symptomatic anterior circulation stenosis or occlusion were retrospectively analyzed. Among them, 8 cases underwent endovascular stenting, 1 case underwent internal carotid endarterectomy and 6 cases received superficial temporal arterial-middle cerebral artery bypass grafting. The regional cerebral blood flow (rCBF) measured by xenon CT and the score of modified Rankin scale mRS6 months after operation were compared. Results the mean r CBF value of 12 patients with abnormal blood perfusion at the distal end of target blood vessel before and after operation was 30 鹵10)ml/(100 / min and 32 鹵14)ml/(100 / min, respectively. The mean r CBF value of 3 patients with normal blood flow perfusion at the distal end of target vessel before operation was 48 鹵6)ml/(100 g / min, and the mean r CBF value was 50 鹵7)ml/(100 g / min after operation. There was no significant difference between before and after operation (P 0. 05 鹵0. 05 g / min) mRS score was improved in 8 cases after operation, and there was no significant difference between before and after operation (P 0. 05 鹵0. 05%, P 0. 05%, P 0. 05%, P 0. 05%, P 0. 05%). The mRS score of 7 cases (15 cases) of stable patients after operation was [1 0 0 3], which was compared with that of preoperative [31% 3]. No new neurological dysfunction was found during follow-up. Conclusion revascularization can improve the distance of target vessels in patients with symptomatic anterior circulation stenosis or occlusion with hemodynamic disorders before operation. Regional cerebral blood perfusion and neurological deficit symptoms, Preoperative xenon CT perfusion perfusion may be more beneficial than normal perfusion.
【作者單位】： 廣東省中醫(yī)院神經(jīng)外科;
【分類號】：R651.12

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本文編號：1692937