本文選題：身高　切入點(diǎn)：體重　出處：《吉林大學(xué)》2015年碩士論文

【摘要】：目的： 這篇文章主要是研究身高、體重、年齡、BMI、性別對于踝關(guān)節(jié)軟骨厚度的影響，并通過與膝關(guān)節(jié)軟骨厚度變化趨勢的影響進(jìn)行對比，分析其相同之處及不同之處，并分析其內(nèi)在原因。 材料與方法： 從2011年1月份至2014年12月份，共有145名患者在吉林大學(xué)中日聯(lián)誼醫(yī)院進(jìn)行踝關(guān)節(jié)核磁共振檢查，通過嚴(yán)格的篩選，沒有踝關(guān)節(jié)軟骨損傷的患者被作為踝關(guān)節(jié)軟骨正常人進(jìn)行入組，共有99個(gè)患者滿足我們的納入標(biāo)準(zhǔn)。我們使用踝關(guān)節(jié)核磁共振圖像來進(jìn)行踝關(guān)節(jié)軟骨厚度的測量，以身高與踝關(guān)節(jié)軟骨厚度之間的關(guān)系、體重與踝關(guān)節(jié)軟骨厚度之間的關(guān)系、BMI與踝關(guān)節(jié)軟骨厚度之間的關(guān)系、年齡與踝關(guān)節(jié)軟骨厚度之間的關(guān)系分別制作散點(diǎn)圖，并以身高、體重、年齡為自變量，以踝關(guān)節(jié)軟骨厚度為因變量做多元線性回歸分析；以BMI為自變量，以踝關(guān)節(jié)軟骨厚度為因變量做一元線性回歸分析。為了進(jìn)一步分析BMI與踝關(guān)節(jié)軟骨厚度之間的關(guān)系，我們將患者樣本分為體重超重組和體重正常組，對兩組踝關(guān)節(jié)平均軟骨厚度進(jìn)行t檢驗(yàn)分析。為了研究性別對踝關(guān)節(jié)軟骨厚度的影響，并去除掉身高對于踝關(guān)節(jié)厚度的影響，我們選取身高在160cm至170cm之間的患者樣本，按性別分為兩組，，對兩組平均軟骨厚度進(jìn)行t檢驗(yàn)。 結(jié)果： 按照多元線性回歸分析以及一元線性回歸分析的結(jié)果，只有身高與踝關(guān)節(jié)軟骨厚度之間有相關(guān)性（P＜0.01），并成正相關(guān)。體重、BMI、年齡與踝關(guān)節(jié)軟骨厚度之間沒有相關(guān)性（P＞0.05）。踝關(guān)節(jié)軟骨厚度在體重正常組（18.5BMI24）與體重超重組（BMI＞24）之間并沒有統(tǒng)計(jì)學(xué)差異（P＞0.05）。當(dāng)患者身高限定在160cm至170cm之間時(shí)，男女兩組身高和踝關(guān)節(jié)軟骨厚度都由統(tǒng)計(jì)學(xué)差異（P＜0.05）。為了平衡掉身高對于踝關(guān)節(jié)軟骨厚度的影響，我們限制男性組最高身高170cm，并不限制男性組最低身高；女性組不限制最高身高，最低身高設(shè)定在160cm。這時(shí)，兩組身高仍有統(tǒng)計(jì)學(xué)差異（P＜0.05）。因此我們逐次提高女性組最低身高限制，我們嘗試161cm和162cm，當(dāng)女性最低身高限制在162cm時(shí)兩組身高沒有統(tǒng)計(jì)學(xué)差異（P＞0.05），因此我們將男性最高身高限制在170cm，女性最低身高限制在162cm，此時(shí)兩組無論身高和軟骨厚度均沒有統(tǒng)計(jì)學(xué)差異（P＞0.05） 結(jié)論： 踝關(guān)節(jié)軟骨厚度主要和身高有關(guān)，跟體重、年齡、BMI、性別都沒有相關(guān)性。這表明，踝關(guān)節(jié)軟骨厚度主要是由發(fā)育決定的，并不會隨年齡的增長有明顯的磨損。由于踝關(guān)節(jié)軟骨與膝關(guān)節(jié)軟骨的生物力學(xué)特性與生物化學(xué)特性不同，因此踝關(guān)節(jié)骨關(guān)節(jié)炎患病率并不會像膝關(guān)節(jié)那樣隨著年齡增長而增大。男性與女性的踝關(guān)節(jié)軟骨厚度沒有明顯差異，因此男性和女性的踝關(guān)節(jié)骨關(guān)節(jié)炎患病率沒有明顯差異。
[Abstract]:Objective:. This article mainly studies the influence of height, weight, age and sex on the thickness of ankle cartilage, and analyzes its similarities and differences by comparing with the change trend of cartilage thickness of knee joint. And analyze its internal reason. Materials and methods:. From January 2011 to December 2014, 145 patients underwent an MRI examination of the ankle joint at the Sino-Japanese Friendship Hospital of Jilin University, and passed strict screening. Patients without ankle cartilage injuries were included as normal ankle cartilage, and 99 patients met our inclusion criteria. We used MRI images to measure the thickness of ankle cartilage. The relationship between height and the thickness of ankle cartilage, the relationship between weight and thickness of ankle cartilage, and the relationship between BMI and thickness of ankle cartilage, the relationship between age and thickness of ankle cartilage, and the relationship between age and the thickness of ankle cartilage were made. Weight, age as independent variables, ankle cartilage thickness as dependent variable for multiple linear regression analysis, BMI as independent variable, In order to further analyze the relationship between BMI and ankle cartilage thickness, we divided the patients into overweight and normal weight groups. In order to study the influence of height on the thickness of ankle cartilage and remove the influence of height on the thickness of ankle joint, we selected a sample of patients whose height was between 160cm and 170cm. Two groups were divided into two groups according to sex. T test was performed on the mean cartilage thickness of the two groups. Results:. According to the results of multivariate linear regression analysis and univariate linear regression analysis, There was only a correlation between height and the thickness of ankle cartilage (P < 0.01) and a positive correlation. There was no correlation between age and cartilage thickness of ankle joint (P > 0.05). The thickness of ankle cartilage was found between normal weight group (18.5BMI24) and overweight BMI > 24 (P > 24). There was no statistical difference (P > 0.05). When the height of the patient was between 160cm and 170cm, In order to balance the effect of height on the thickness of ankle cartilage, we limited the maximum height of the male group to 170 cm, not the minimum height of the male group; the female group did not limit the maximum height. The minimum height was set at 160 cm. At this time, there was still a significant difference in height between the two groups (P < 0.05). So we raised the minimum height limit of the female group one by one. We tried 161cm and 162cm, when the minimum height of women was limited to 162cm, there was no significant difference in height between the two groups (P > 0.05), so we limited the maximum height of men to 170 cm and the minimum height of women to 162 cm. In this case, both groups were of both height and cartilage thickness. There was no statistical difference (P > 0.05). Conclusion:. The thickness of ankle cartilage is mainly related to height, but not to weight, age and sex. This indicates that the thickness of ankle cartilage is mainly determined by development. There is no obvious wear with age. Because the biomechanical and biochemical properties of ankle cartilage and knee cartilage are different, Therefore, the incidence of ankle osteoarthritis does not increase with age as the knee joint. There is no significant difference in the thickness of ankle cartilage between men and women, so there is no significant difference between men and women in the prevalence of ankle osteoarthritis.
【學(xué)位授予單位】：吉林大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2015
【分類號】：R684.3

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