本文選題：燒傷創(chuàng)面　切入點：Meek植皮　出處：《南昌大學(xué)》2017年碩士論文

【摘要】：背景:大面積深度燒傷病人大部分皮膚被破壞,燒傷創(chuàng)面暴露于外界,急需自體皮膚移植,但這類病人的自體移植皮源匱乏,Meek植皮與微粒皮植皮是救治這類燒傷病人的主要手段,近十年以來,關(guān)于Meek植皮術(shù)的臨床療效陸續(xù)被報道,但是與微粒皮植皮的臨床對照研究的優(yōu)劣勢存在爭議,這些研究大部分樣本量小,缺乏說服力。目的:Meek植皮術(shù)與微粒皮植皮術(shù)在修復(fù)大面積深度燒傷創(chuàng)面的臨床療效及應(yīng)用價值進行系統(tǒng)性評價。方法:用計算機以“Meek micrografting technique”AND“microskin graft methods”等為檢索詞檢索PubMed(1990/2016-10)、Ovid(1966/2016-10)、Elsevier(1988/2016-10)、SPRINGER(1995/2016-10)、The Cochrane Library(1978/2016-10)數(shù)據(jù)庫,以“Meek植皮”和“微粒皮”及“燒傷/burn”為關(guān)鍵檢索詞檢索萬方數(shù)據(jù)庫(1982/2016)、維普中文科技期刊數(shù)據(jù)庫(1979/2016)和中國知網(wǎng)數(shù)據(jù)庫(CNKI,1979/2016),并挑選并收集與Meek植皮術(shù)與微粒皮植皮術(shù)相關(guān)治療大面積深度燒傷創(chuàng)面的臨床對照研究(CCT)。評價納入研究的文獻質(zhì)量,關(guān)鍵資料收集后,使用RevMan 5.1軟件行Meta分析。結(jié)果與結(jié)論:共納入8個臨床對照研究,包含302例大面積燒傷患者。相比于微粒皮植皮組,Meek植皮組在皮片存活率顯著增加,在創(chuàng)面愈合時間、皮片融合時間、手術(shù)操作時間及1%燒傷面積治療費用均明顯降低,表明Meek植皮術(shù)比微粒皮植皮術(shù)更能明顯增加皮片存活率并促進創(chuàng)面愈合,縮短手術(shù)操作時間,并且減少治療費用,在臨床應(yīng)用價值更加有優(yōu)勢。
[Abstract]:Background: large area deep burn patients are mostly damaged, the burn wounds are exposed to the outside world, and autologous skin transplantation is urgently needed. However, Meek skin grafts and microskin grafts are the main methods to treat these burn patients. In the past ten years, the clinical effects of Meek skin grafting have been reported one after another. But there is controversy about the merits and demerits of clinical comparative studies with microskin grafts, most of which are small in size. Objective: to evaluate systematically the clinical efficacy and application value of Meek Meek skin grafting and microskin skin grafting in the repair of large area deep burn wounds. Methods: the computer was used to search the database of the Cochrane Library 1978-10 using "Meek micrografting technique" AND "microskin graft methods". Using "Meek skin grafting" and "Particle skin" and "Burn / Burn" as the key keywords to search Wanfang Database / 1982 / 2016, Weipu Chinese Science and Technology Journal Database / 1979 / 2016) and China knowledge Network Database to select and collect the images of Meek skin grafting and Particle skin grafting. A clinical controlled study on the treatment of large area deep burn wounds by Guan. Evaluation of the quality of literature included in the study. After the key data were collected, Meta analysis was performed with RevMan 5.1 software. Results and conclusion: eight clinical controlled studies were conducted, including 302 patients with large area burn. The survival rate of skin grafts in the Meek skin graft group was significantly higher than that in the microskin graft group. The time of wound healing, the time of skin graft fusion, the time of operation and the cost of treatment of 1% burn area were significantly decreased. The results showed that Meek skin grafting could significantly increase the survival rate of skin grafts and promote wound healing. Shortening the time of operation and reducing the cost of treatment is more valuable in clinical application.
【學(xué)位授予單位】：南昌大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2017
【分類號】：R644

【參考文獻】

相關(guān)期刊論文 前10條

1 李云飛;龍曉東;李永忠;;Meek植皮術(shù)修復(fù)大面積重度燒傷創(chuàng)面的療效觀察[J];貴州醫(yī)科大學(xué)學(xué)報;2016年09期

2 張桂全;張珊珊;劉志會;;大面積深度燒傷應(yīng)用微粒皮移植技術(shù)與Meek植皮技術(shù)治療的比較[J];中國醫(yī)藥指南;2016年17期

3 于攀;汪軍;洪志堅;姜會慶;;可吸收性生物敷料在特大面積深度燒傷患者膝部創(chuàng)面修復(fù)中的應(yīng)用[J];第三軍醫(yī)大學(xué)學(xué)報;2015年19期

4 葉勝捷;張文振;龐淑光;陳如俊;葉鸝柳;方聲教;章錦成;方慶偉;謝瑞章;;應(yīng)用Meek微型皮片移植術(shù)修復(fù)老年成批大面積燒傷創(chuàng)面的療效觀察[J];中華損傷與修復(fù)雜志(電子版);2015年03期

5 張明珠;王建華;歷虎;董運鳳;齊長春;郭寶文;王永嶺;劉曉巖;李云峰;張曉慧;劉穎;李興華;王鴻風(fēng);郁強;;異種皮覆蓋薄中厚與刃厚微粒皮皮漿移植修復(fù)燒傷創(chuàng)面的對比[J];中國組織工程研究;2014年46期

6 陳驥揚;孫東原;孟暉;賴雪娜;;Meek植皮術(shù)及微粒皮移植術(shù)在特大面積深度燒傷創(chuàng)面治療中的效果比較[J];當(dāng)代醫(yī)學(xué);2014年09期

7 朱恩全;李祥;王曉雁;聞紅貴;岳旭文;;不同植皮技術(shù)治療大面積深度燒傷創(chuàng)面的效果比較[J];當(dāng)代醫(yī)學(xué);2014年02期

8 明志國;雷晉;段鵬;成劍;魏太平;陳忠江;郭萬里;王建明;;Meek植皮技術(shù)與微粒皮移植技術(shù)在大面積深度燒傷創(chuàng)面治療中的對照研究[J];中華損傷與修復(fù)雜志(電子版);2013年03期

9 劉洋;包校偉;袁華;吳忠好;廖紅;孔偉立;夏雄;;Meek植皮術(shù)治療特大面積深度燒傷的臨床價值[J];實用臨床醫(yī)藥雜志;2013年01期

10 牛利斌;王甲漢;黃磊;劉霞;謝艷平;邱學(xué)文;;影響大面積燒傷患者預(yù)后的相關(guān)因素分析[J];廣東醫(yī)學(xué);2012年13期

相關(guān)會議論文 前1條

1 林才;楊寧;張鵬;陳更新;徐建軍;羅旭;劉政軍;;Meek植皮法與微粒皮植皮法治療大面積燒傷的經(jīng)濟學(xué)比較初探[A];浙江省第十七屆燒傷外科學(xué)學(xué)術(shù)會議論文匯編[C];2007年

，

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