本文選題：胃腸道惡性腫瘤　切入點(diǎn)：聽覺詞語學(xué)習(xí)測驗(yàn)(AVLT)　出處：《福建醫(yī)科大學(xué)》2015年碩士論文　論文類型：學(xué)位論文

【摘要】：目的對比分析老年胃腸道惡性腫瘤與非惡性腫瘤老患者認(rèn)知功能的差別,為臨床的進(jìn)一步研究防治術(shù)后認(rèn)知功能障礙提供前期研究結(jié)果。方法采用聽覺詞語學(xué)習(xí)測驗(yàn)(AVLT)和畫鐘實(shí)驗(yàn)(CDT)兩種神經(jīng)心理測驗(yàn)方法,對2014年11月至2015年1月期間在福建醫(yī)科大學(xué)附屬協(xié)和醫(yī)院住院的73名60歲至80歲的胃腸道惡性腫瘤老年患者(A組)與47名同年齡段的非惡性腫瘤老年患者(B組)的認(rèn)知功能進(jìn)行評估,并記錄患者的臨床資料,包括病案號、年齡、性別、受教育程度、內(nèi)科合并癥等,兩組患者的基本資料以及評估結(jié)果根據(jù)正態(tài)性檢驗(yàn)結(jié)果分別利用獨(dú)立樣本t檢驗(yàn)、卡方檢驗(yàn)、秩和檢驗(yàn)和R*C表資料的卡方檢驗(yàn)進(jìn)行統(tǒng)計(jì)學(xué)分析,進(jìn)一步比較二者間的差異。結(jié)果A、B兩組病例在年齡、性別組成、受教育程度及內(nèi)科合并癥等方面的差異無統(tǒng)計(jì)學(xué)意義(P0.05);A組的短時(shí)刻記憶(AVLT-1、AVLT-2、AVLT-3、AVLT-I)、短延遲回憶(AVLT-4)與AVLT總分明顯低于B組,A組的認(rèn)知功能障礙發(fā)生率(43.83%)明顯高于B組(25.53%),差異均有統(tǒng)計(jì)學(xué)意義(P0.05),但A組患者的長延遲記憶得分(AVLT-5)、AVLT-E、AVLT再認(rèn)及CDT得分與B組的差異無統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論胃腸道惡性腫瘤患者認(rèn)知功能損害較非惡性腫瘤患者明顯,且認(rèn)知損害主要表現(xiàn)在短時(shí)刻記憶和短延遲回憶。
[Abstract]:Objective to compare and analyze the difference of cognitive function between elderly patients with gastrointestinal malignancies and those with non-malignant tumors. Methods two neuropsychological test methods: auditory word learning test (AVLT) and bell drawing test (CDT) were used. From November 2014 to January 2015, 73 elderly patients aged 60 to 80 with gastrointestinal malignancies were hospitalized in Union Hospital of Fujian Medical University) and 47 non-malignant elderly patients of the same age were treated with Group B). To assess cognitive function, The clinical data of the patients were recorded, including medical record number, age, sex, education level, medical complications and so on. The basic data and evaluation results of the two groups were tested by independent sample t test and chi-square test according to the results of normality test. Rank sum test and chi-square test were used to further compare the difference between the two groups. Results the age, sex composition of two groups of patients were analyzed. There was no significant difference in education level and complication of internal medicine. The total scores of AVLT-1, AVLT-2, AVLT-3, AVLT-4 and AVLT in group A were significantly lower than those in group B (43.833) and significantly higher than that in group B (25.533.35), and the total scores of AVLT-4 and AVLT in group A were significantly lower than those in group B (43.833). There was no significant difference between group A and group B in the recognition of AVLT-E AVLT and the scores of CDT. Conclusion the cognitive impairment in patients with gastrointestinal malignancy is significantly higher than that in patients with non-malignant tumors. And cognitive impairment mainly manifested in short-time memory and short-delayed memory.
【學(xué)位授予單位】：福建醫(yī)科大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2015
【分類號】：R614;R735

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