本文選題：神經(jīng)鞘瘤　切入點(diǎn)：惡性外周神經(jīng)鞘瘤　出處：《臨床放射學(xué)雜志》2017年06期 　論文類型：期刊論文

【摘要】：目的探討脊柱區(qū)良惡性神經(jīng)鞘瘤的影像表現(xiàn),以提高對(duì)此類腫瘤的認(rèn)識(shí)。方法對(duì)21例臨床病理確診的神經(jīng)鞘瘤和16例惡性外周神經(jīng)鞘瘤(MPNST)的影像表現(xiàn)進(jìn)行對(duì)比分析并對(duì)影像特點(diǎn)采用非參數(shù)檢驗(yàn)進(jìn)行統(tǒng)計(jì)分析。結(jié)果 21例神經(jīng)鞘瘤和16例MPNST分別位于頸椎(12例,57.1%;9例,56.3%)、胸椎(5例,23.8%;2例,12.5%)和腰骶椎(4例,19%;5例,31.3%);21例神經(jīng)鞘瘤均伴骨破壞,19例邊界清晰,14例伴硬化邊形成,19例伴骶孔或椎間孔擴(kuò)大;16例MPNST中13例伴骨破壞,4例邊界清晰,2例伴硬化邊,8例伴骶孔或椎間孔擴(kuò)大;二組腫瘤在邊界(χ~2=4.7,P=0.001)、硬化邊(χ~2=10.9,P=0.001)、骶孔或椎間孔擴(kuò)大(χ~2=7.5,P=0.006)存在統(tǒng)計(jì)學(xué)差異;MRI信號(hào)及增強(qiáng)特點(diǎn)無統(tǒng)計(jì)學(xué)差異(P0.05)。結(jié)論神經(jīng)鞘瘤和MPNST均可伴骨破壞,其骨破壞特點(diǎn)存在一定差異;MRI信號(hào)及增強(qiáng)特點(diǎn)相似,對(duì)二者的鑒別診斷意義有限。
[Abstract]:Objective to investigate the imaging features of benign and malignant neurilemmoma in spinal area. Methods the imaging features of 21 cases of clinicopathologically diagnosed neurilemmoma and 16 cases of malignant peripheral neurilemmoma were compared and analyzed by non-parametric test. Results 21 cases of neurilemmoma and 16 cases of MPNST were located in cervical vertebrae in 12 cases (57.1%), thoracic vertebrae in 5 cases (23.8%) and lumbosacral foramen in 2 cases (12.5%) and lumbosacral foramen in 4 cases (5 cases), 21 cases of schwannoma of lumbosacral vertebrae (5 cases) with bone destruction, 14 cases with clear border of sclerosis with sclerotic margin and 19 cases with sacral foramen. Or intervertebral foramina enlargement in 16 cases of MPNST 13 cases with bone destruction 4 cases with clear boundary 2 cases with sclerosing side of 8 cases with sacral foramen or intervertebral foramina enlargement; There was no significant difference in MRI signal and enhancement between the two groups (蠂 ~ 2 ~ (2) ~ (4) ~ (7) ~ (7) ~ (7) ~ (th)), sclerosing side (蠂 ~ (210.9) P ~ (0.001)), enlargement of sacral foramen or intervertebral foramen (蠂 ~ (2) ~ (2)), and no significant difference in Mr signal and enhancement. Conclusion both neurilemmoma and MPNST can be accompanied by bone destruction. There are some differences in the characteristics of bone destruction between MRI and MRI, which is of limited significance in differential diagnosis.
【作者單位】： 北京大學(xué)第三醫(yī)院放射科;首都醫(yī)科大學(xué)電力教學(xué)醫(yī)院放射科;
【分類號(hào)】：R730.44;R738

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