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乳腺背景實(shí)質(zhì)強(qiáng)化與月經(jīng)狀態(tài)、月經(jīng)周期及乳腺纖維腺體組織含量關(guān)系的研究

發(fā)布時(shí)間:2018-03-09 19:41

  本文選題:乳腺背景實(shí)質(zhì)強(qiáng)化 切入點(diǎn):月經(jīng)狀態(tài) 出處:《臨床放射學(xué)雜志》2017年12期  論文類型:期刊論文


【摘要】:目的探討乳腺增強(qiáng)磁共振背景實(shí)質(zhì)強(qiáng)化(BPE)與月經(jīng)狀態(tài)、月經(jīng)周期及乳腺纖維腺體組織(FGT)含量之間的關(guān)系。方法回顧性分析150例女性受檢者的乳腺動(dòng)態(tài)增強(qiáng)磁共振成像(DCE-MRI)資料。根據(jù)月經(jīng)狀態(tài)(絕經(jīng)前和絕經(jīng)后)及受檢時(shí)所處月經(jīng)周期的周數(shù)(1~4周)將受檢者分組。BPE分為四級(jí):極少量、少量、中等量、大量。在DCE-MRI掃描早期(89 s)定性評(píng)估BPE,在早期及晚期(449 s)定量計(jì)算雙側(cè)乳腺背景實(shí)質(zhì)強(qiáng)化的增長(zhǎng)率(BPER=SI_(post)-S_(Ipre)/SI_(pre)),并與FGT含量進(jìn)行相關(guān)性分析。結(jié)果 BPE與月經(jīng)狀態(tài)之間具有明顯相關(guān)性(r=0.677),絕經(jīng)前組BPER高于絕經(jīng)后組,兩者差異具有統(tǒng)計(jì)學(xué)意義(P0.05)。絕經(jīng)前、后組的BPE與FGT含量之間均呈弱相關(guān)性(r=0.321)。月經(jīng)周期后半階段(第3、4周)定性BPE及定量BPER較前半階段(第1、2周)高。增強(qiáng)晚期BPER高于早期,差異具有統(tǒng)計(jì)學(xué)意義(P0.05)。雙側(cè)乳腺BPER的差異無(wú)統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論 BPE與月經(jīng)狀態(tài)之間具有明顯相關(guān)性(絕經(jīng)后女性強(qiáng)化低于絕經(jīng)前)。BPE與月經(jīng)周期具有明顯相關(guān)性;在月經(jīng)周期的前半階段(第1~2周),BPE較低,推薦在此期間進(jìn)行乳腺M(fèi)RI檢查。FGT含量與BPE之間沒(méi)有明顯相關(guān)性。
[Abstract]:Objective to investigate the relationship between mammary gland enhanced magnetic resonance imaging background background enhancement and menstrual status. Relationship between menstrual cycle and the content of FGTs in fibrous glands of mammary glands. Methods DCE-MRI data of 150 female subjects were analyzed retrospectively. According to the menstrual state (premenopausal and postmenopausal) and the examined data, the data of DCE-MRI were analyzed retrospectively. The number of weeks of the menstrual cycle in which the period occurs is 1 / 4 weeks). BPE is divided into four levels: a very small number, Small, medium, In the early stage of DCE-MRI scanning, the qualitative assessment of BPE49 s, and in the early and late stage of 449 s), the quantitative calculation of the growth rate of bilateral breast background substantive enhancement was carried out, and the correlation analysis between BPE and menstrual state was carried out, and the correlation between BPE and menstrual state was analyzed. The BPER of premenopausal group was higher than that of postmenopausal group. The difference was statistically significant (P 0.05). There was a weak correlation between the content of BPE and FGT in premenopausal and postmenopausal groups. The qualitative BPE and quantitative BPER were higher in the second half of the menstrual cycle (3 ~ 4 weeks) than in the first half period (1 ~ 2 weeks). The difference was statistically significant (P 0.05). There was no significant difference in bilateral breast BPER. Conclusion there is a significant correlation between BPE and menstrual state (postmenopausal women's enhancement is lower than that of premenopausal women's. BPE and menstrual cycle. During the first half of the menstrual cycle (the 1st week 2 weeks), it is recommended that there is no significant correlation between the breast MRI examination and BPE during the first half of the menstrual cycle.
【作者單位】: 昆明醫(yī)科大學(xué)第三附屬醫(yī)院云南省腫瘤醫(yī)院放射科;
【分類號(hào)】:R445.2;R737.9

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