本文選題：椎體成形術　切入點：磷酸鈣類　出處：《中國組織工程研究》2017年14期 　論文類型：期刊論文

【摘要】：背景:椎體成形是治療骨質疏松性椎體壓縮骨折安全、有效的微創(chuàng)治療技術。目的:綜述椎體成形中骨充材料的生物力學性能、骨強度維持狀態(tài)、骨降解吸收及誘導成骨等方面的研究進展。方法:第一作者應用計算機檢索中國知網、PubMed、Medline數(shù)據(jù)庫2005年1月至2016年5月的相關文章,英文檢索詞為"Bone cement;Bone filling materials;Percutaneous vertebroplasty",中文檢索詞為"骨水泥;骨填充材料;椎體成形術"。結果與結論:聚甲基丙烯酸甲酯骨水泥不是骨質疏松性椎體壓縮骨折椎體填充的理想材料。磷酸鈣骨水泥和硫酸鈣骨水泥可替代傳統(tǒng)聚甲基丙烯酸甲酯骨水泥,但磷酸鈣骨水泥和硫酸鈣骨水泥也存在一些問題,如顯影效果不理想、生物降解速度難以控制、遠期效果缺乏進一步循證醫(yī)學的支持等。復合骨水泥兼顧了多種骨水泥的優(yōu)點,是良好的骨修復材料,但進入臨床時間短,還需大量的臨床實踐證明,是目前研究的主要方向。
[Abstract]:Background: vertebroplasty is a safe and effective minimally invasive technique for the treatment of osteoporotic vertebral compression fractures. Objective: to review the biomechanical properties and bone strength maintenance of bone filling materials in vertebroplasty. Advances in bone degradation and osteogenesis methods: the first author used a computer to search the relevant articles in the PubMedline database of China from January 2005 to May 2016. The English key word is "Bone cemented bone filling material vertebroplasty", the Chinese key word is "bone cement, bone filling material material", and the Chinese key word is "bone cement; bone filling material". Results & conclusion: polymethyl methacrylate bone cement is not an ideal material for vertebral body filling in osteoporotic vertebral compression fracture. Calcium phosphate cement and calcium sulfate cement can replace traditional polymethyl methacrylate cement. However, there are some problems in calcium phosphate cement and calcium sulfate cement, for example, the development effect is not ideal, the biodegradation rate is difficult to control, the long-term effect is short of the support of further evidence-based medicine and so on. The composite bone cement takes into account the advantages of many kinds of bone cement. It is a good bone repair material, but the clinical time is short and a lot of clinical practice is needed. It is the main research direction at present.
【作者單位】： 成都體育學院;四川省骨科醫(yī)院;
【基金】：四川省科技廳支撐計劃(2015SZ0190) 國家科技支撐計劃(2012BAK21B01-02)~~
【分類號】：R318.08;R687.3

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