本文關(guān)鍵詞： 脊柱骨折 骨質(zhì)疏松 激素誘導(dǎo) 再發(fā)骨折　出處：《重慶醫(yī)學(xué)》2017年27期 　論文類型：期刊論文

【摘要】：目的探討激素誘導(dǎo)骨質(zhì)疏松性胸腰椎體骨折患者行經(jīng)皮椎體成形術(shù)(PVP)后再發(fā)骨折的危險因素。方法選取2010年4月至2015年7月解放軍第425中心醫(yī)院收治的骨質(zhì)疏松性胸腰椎體骨折患者646例,根據(jù)骨折類型分為原發(fā)性骨質(zhì)疏松性胸腰椎體骨折(n=542)和激素誘導(dǎo)骨質(zhì)疏松性胸腰椎體骨折(n=104),比較兩組患者的再發(fā)骨折發(fā)生率。根據(jù)再發(fā)骨折發(fā)生情況將激素誘導(dǎo)骨質(zhì)疏松性胸腰椎體骨折患者分為骨折組和無骨折組,對兩組患者的臨床資料進(jìn)行單因素和多因素Logistic回歸分析。結(jié)果原發(fā)性骨質(zhì)疏松性胸腰椎體骨折患者再發(fā)骨折102例(18.82%),激素誘導(dǎo)骨質(zhì)疏松性胸腰椎骨折患者再發(fā)骨折53例(50.96%)。骨折組和無骨折組患者的體質(zhì)量指數(shù)、骨密度、骨水泥滲漏、術(shù)前椎體裂隙樣變、未接受抗骨質(zhì)疏松治療比例差異有統(tǒng)計(jì)學(xué)意義(P0.05)。骨密度、骨水泥滲漏、術(shù)前椎體裂隙樣變、未接受抗骨質(zhì)疏松治療是影響激素誘導(dǎo)骨質(zhì)疏松性胸腰椎體骨折患者行PVP后再發(fā)骨折的獨(dú)立危險因素(P0.05)。結(jié)論激素誘導(dǎo)骨質(zhì)疏松性胸腰椎體骨折患者再發(fā)骨折風(fēng)險較高,骨密度、骨水泥滲漏、術(shù)前椎體裂隙樣變、是否接受抗骨質(zhì)疏松治療等是再發(fā)骨折的主要危險因素。
[Abstract]:Objective to investigate the risk factors of recurrent fracture after percutaneous vertebroplasty (PVP) in patients with osteoporotic thoracolumbar vertebral fracture induced by hormone. Methods Osteoporosis was selected from April 2010 to July 2015 in the 425th Central Hospital of PLA. 646 cases of thoracolumbar vertebral fracture, According to the type of fracture, the patients were divided into primary osteoporotic thoracolumbar vertebra fracture and steroid-induced thoracolumbar vertebral fracture. The incidence of recurrent fracture was compared between the two groups. The hormone was induced by hormone according to the occurrence of recurrent fracture. Patients with osteoporotic thoracolumbar vertebral body fracture are divided into fracture group and non-fracture group. The clinical data of the two groups were analyzed by univariate and multivariate Logistic regression analysis. Results 102 cases of recurrent fracture of primary osteoporotic thoracolumbar vertebral body fracture were treated with hormone induced osteoporotic thoracolumbar vertebra fracture. Body mass index (BMI) of 53 patients with fracture and without fracture, Bone mineral density (BMD), bone cement leakage (BMD), bone cement leakage (BMD), vertebral fissure like change before operation, no anti-osteoporosis treatment were significantly different (P < 0.05), bone mineral density (BMD), bone cement leakage (BMD), vertebral fissure like change before operation (P < 0.05), No anti-osteoporosis treatment was an independent risk factor for the recurrence of osteoporotic thoracolumbar vertebral fractures after PVP. Conclusion the risk of recurrent fractures in patients with steroid induced osteoporotic thoracolumbar vertebral fractures is higher and bone mineral density is higher than that in patients with steroid induced osteoporotic thoracolumbar vertebral fractures. The main risk factors for recurrent fracture are cement leakage, vertebral fissure-like change before operation and anti-osteoporosis treatment.
【作者單位】： 中國人民解放軍第425中心醫(yī)院脊柱骨科;海南醫(yī)學(xué)院附屬醫(yī)院骨科;
【基金】：國家自然科學(xué)基金資助項(xiàng)目(81260271)
【分類號】：R580;R687.3
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本文編號：1533615