本文關(guān)鍵詞： 黏膜病變 胃食管連接部 胃鏡黏膜下剝離術(shù) 胃鏡檢查　出處：《中華實(shí)用診斷與治療雜志》2016年11期 　論文類型：期刊論文

【摘要】：目的探討胃鏡黏膜下剝離術(shù)(endoscopic submucosal dissection,ESD)治療胃食管連接部黏膜病變的療效及安全性。方法回顧性分析30例胃食管連接部黏膜病變患者臨床資料,分析病變特點(diǎn)及ESD治療切除率和手術(shù)時(shí)間,隨訪觀察術(shù)后并發(fā)癥和復(fù)發(fā)情況。結(jié)果患者胃食管連接部黏膜病變直徑(30±15)mm,ESD治療完整切除率為100%,手術(shù)時(shí)間(45±16)min;術(shù)后1例有少量胃管內(nèi)出血,未發(fā)生穿孔等并發(fā)癥;組織病理確診黏膜慢性炎癥8例,萎縮性胃炎3例,增生性息肉6例,低級(jí)別上皮內(nèi)瘤變9例,高級(jí)別上皮內(nèi)瘤變3例,腺癌1例;平均隨訪18個(gè)月,無復(fù)發(fā)。結(jié)論 ESD治療胃食管連接部黏膜病變的完整切除率高,安全。
[Abstract]:Objective to investigate endoscopic submucosal dissection in submucosal dissection. Methods the clinical data of 30 patients with gastroesophageal junction mucosal lesions were retrospectively analyzed. The characteristics of the lesions, the resection rate and the operation time of ESD were analyzed, and the postoperative complications and recurrence were observed. Results the diameter of mucosal lesions in the gastroesophageal junction was 30 鹵15mm. The complete resection rate of ESD was 100 and the operation time was 45 鹵16 minutes. There was a small amount of intragastric hemorrhage in 1 case, and no complications such as perforation occurred. 8 cases of chronic inflammation of mucosa, 3 cases of atrophic gastritis, 6 cases of proliferative polyps, 9 cases of low grade intraepithelial neoplasia, 3 cases of high grade intraepithelial neoplasia and 1 case of adenocarcinoma were confirmed by histopathology. Conclusion the complete resection rate of ESD for gastroesophageal junction mucosal lesions is high and safe.
【作者單位】： 江陰市中醫(yī)院內(nèi)鏡中心;復(fù)旦大學(xué)附屬中山醫(yī)院內(nèi)鏡中心;
【基金】：國家自然科學(xué)基金(81370588)
【分類號(hào)】：R655.4
【正文快照】： 胃食管連接部是鱗狀上皮及柱狀上皮交匯處,為食管與胃結(jié)合部位,管腔狹窄且為銳性轉(zhuǎn)角,其特殊的解剖結(jié)構(gòu)可增加術(shù)后并發(fā)癥發(fā)生率[1]。胃食管連接部病變臨床多采用開腹或腹腔鏡手術(shù),但術(shù)后可引起胃食管反流等。隨著胃鏡技術(shù)發(fā)展,臨床對(duì)病變局限于上皮內(nèi)、且無淋巴結(jié)轉(zhuǎn)移的癌前病

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本文編號(hào)：1491984