本文關(guān)鍵詞： 骨質(zhì)疏松 骨密度 骨關(guān)節(jié)退行性疾病　出處：《中國骨質(zhì)疏松雜志》2017年05期 　論文類型：期刊論文

【摘要】：目的探討絕經(jīng)后女性不同骨關(guān)節(jié)退行性疾病的臨床特點及與骨密度的關(guān)系,為防治絕經(jīng)后骨關(guān)節(jié)退行性疾病提供依據(jù)。方法選取2013年9月至2016年3月在我院收治的959例絕經(jīng)后女性患者,取腰椎和股骨頸處的最大的骨密度值及T值作為研究對象,按不同骨關(guān)節(jié)退行性疾病分為脆性骨折組、腰椎退行性病變組、膝骨關(guān)節(jié)炎組及無明顯骨關(guān)節(jié)疾病對照組。采用SPSS 19.0軟件進行統(tǒng)計學分析。結(jié)果 (1)各組間腰椎BMD值及T值的差異具有統(tǒng)計學意義(P0.05),其中腰椎退行性病變組患者的腰椎骨密度值和T值均比其他3組明顯減低(P0.05),膝骨關(guān)節(jié)炎組骨密度值和T值均高于其他3組(P0.05);(2)各組間股骨頸BMD值及T值的差異具有統(tǒng)計學意義(P0.05),其中脆性骨折組患者的股骨頸骨密度值和T值均比其他3組明顯減低(P0.05),膝骨關(guān)節(jié)炎組骨密度值和T值均高于其他3組(P0.05)。結(jié)論在絕經(jīng)后女性患者中,脆性骨折與骨質(zhì)疏松的關(guān)系最為密切,而其他骨關(guān)節(jié)疾病也在不同程度上與骨質(zhì)疏松程度存在顯著相關(guān)性,在治療骨關(guān)節(jié)疾病的同時也要重視骨質(zhì)疏松癥的防治。
[Abstract]:Objective to investigate the clinical characteristics of different osteoarticular degenerative diseases in postmenopausal women and their relationship with bone mineral density (BMD). Methods 959 postmenopausal women who were admitted to our hospital from September 2013 to March 2016 were selected to provide evidence for the prevention and treatment of postmenopausal osteoarthritis. The maximum bone mineral density (BMD) and T value of lumbar spine and femoral neck were taken as the research objects. According to different osteoarticular degenerative diseases, they were divided into brittle fracture group and lumbar degenerative disease group. SPSS 19.0 software was used for statistical analysis. Results the BMD and T values of lumbar vertebrae in each group were significantly different (P < 0.05). P0.05). The bone mineral density and T value of lumbar vertebrae in the group of lumbar degenerative diseases were significantly lower than those in the other three groups, and the bone mineral density and T value in the group of knee osteoarthritis were higher than those in the other three groups. (2) the difference of BMD value and T value of femoral neck was statistically significant (P 0.05). The bone mineral density and T value of femoral neck in fragile fracture group were significantly lower than those in other three groups (P 0.05). Bone mineral density (BMD) and T value in knee osteoarthritis group were higher than those in the other three groups (P 0.05). Conclusion in postmenopausal women, brittle fracture is most closely related to osteoporosis. Other bone and joint diseases also have a significant correlation with the degree of osteoporosis in varying degrees. We should pay attention to the prevention and treatment of osteoporosis as well as the treatment of osteoarthrosis.
【作者單位】： 廣州醫(yī)科大學附屬第二醫(yī)院;
【基金】：國家自然科學基金資助(81574002)
【分類號】：R580;R684
【正文快照】： 隨著社會人口老齡化,近年來骨與關(guān)節(jié)的退行性疾病的發(fā)病率越來越高,嚴重影響了人們的生活質(zhì)量,給患者的家庭和整個社會帶來了重大的負擔;而這些骨關(guān)節(jié)疾病常常合并骨質(zhì)疏松癥(osteoporosis,OP),尤其在絕經(jīng)后女性中更為常見。骨密度(bone mineral density,BMD)是診斷骨質(zhì)疏松癥，

本文編號：1480045