肝硬化失代償期患者并發(fā)腸梗阻的臨床特點及相關(guān)危險因素分析
發(fā)布時間:2018-01-24 21:05
本文關(guān)鍵詞: 肝硬化 腸梗阻 臨床特征 危險因素 出處:《上海交通大學(xué)學(xué)報(醫(yī)學(xué)版)》2017年07期 論文類型:期刊論文
【摘要】:目的·分析肝硬化失代償期患者并發(fā)腸梗阻的臨床特點及危險因素。方法·收集2010年3月—2016年3月收治的1 783例肝硬化失代償期患者的臨床資料,篩選出并發(fā)腸梗阻患者128例(7.18%)作為觀察組,隨機(jī)抽取未并發(fā)腸梗阻患者128例作為對照組�;仡櫺匝芯�2組患者的臨床資料,對臨床特征進(jìn)行對比分析,并采用Logistic回歸分析相關(guān)危險因素。結(jié)果·肝硬化失代償期患者并發(fā)腸梗阻的臨床癥狀隱匿,容易被漏診或延遲診斷。觀察組腹痛、腹脹、嘔吐、停止排便排氣、發(fā)熱、自發(fā)性腹膜炎、腹水、電解質(zhì)紊亂的發(fā)生率顯著高于對照組(P0.05)。單因素分析結(jié)果顯示:年齡、腹部手術(shù)史、白細(xì)胞計數(shù)、血清鉀、血清鈉、中性粒細(xì)胞百分比、血清白蛋白為肝硬化失代償期患者并發(fā)腸梗阻的危險因素。進(jìn)一步的多因素回歸分析結(jié)果顯示:年齡、腹部手術(shù)史、白細(xì)胞計數(shù)、血清鉀、血清鈉、中性粒細(xì)胞百分比、血清白蛋白是肝硬化失代償期患者并發(fā)腸梗阻的獨立危險因素。結(jié)論·年齡≥50歲、有腹部手術(shù)史、合并腹腔感染、低鉀、低鈉、低血清白蛋白的肝硬化失代償期患者容易并發(fā)腸梗阻。
[Abstract]:Objective: to analyze the clinical characteristics and risk factors of intestinal obstruction in patients with decompensated cirrhosis from March 2010 to March 2016. Clinical data of 783 patients with decompensated cirrhosis. 128 patients with intestinal obstruction were selected as observation group, 128 patients without intestinal obstruction were randomly selected as control group. The clinical data of two groups were studied retrospectively. The clinical features were compared and analyzed, and Logistic regression analysis was used to analyze the risk factors. Results: the clinical symptoms of intestinal obstruction in patients with decompensated cirrhosis were hidden. Easy to be missed or delayed diagnosis. Observation group abdominal pain, abdominal distension, vomiting, stop defecation and exhaust, fever, spontaneous peritonitis, ascites. The incidence of electrolyte disturbance was significantly higher than that of control group (P 0.05). Univariate analysis showed that age, history of abdominal surgery, white blood cell count, serum potassium, serum sodium, percentage of neutrophils. Further multivariate regression analysis showed that age, history of abdominal surgery, leukocyte count, serum potassium, serum sodium. Percentage of neutrophils and serum albumin were independent risk factors of intestinal obstruction in patients with decompensated cirrhosis. Conclusion: age 鈮,
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