本文關(guān)鍵詞：谷氨酰胺治療對(duì)有營(yíng)養(yǎng)風(fēng)險(xiǎn)肝膽手術(shù)病人臨床結(jié)局影響研究　出處：《中國(guó)實(shí)用外科雜志》2016年01期 　論文類型：期刊論文

  更多相關(guān)文章： 肝膽手術(shù) 營(yíng)養(yǎng)風(fēng)險(xiǎn) 谷氨酰胺

【摘要】：目的觀察肝膽手術(shù)病人營(yíng)養(yǎng)風(fēng)險(xiǎn)的發(fā)生率,探討谷氨酰胺(Glutamine,GLn)治療對(duì)有營(yíng)養(yǎng)風(fēng)險(xiǎn)病人臨床結(jié)局的影響。方法采用隊(duì)列研究的方法,連續(xù)定點(diǎn)采集2011年1月至2014年12月于廣州軍區(qū)武漢總醫(yī)院行手術(shù)治療的肝膽外科病人資料,用NRS2002評(píng)分標(biāo)準(zhǔn),對(duì)≥3分的病人納入研究。共402例病人,分Gln治療組248例和非Gln組154例,觀察兩組住院時(shí)間和感染性并發(fā)癥發(fā)生率。結(jié)果 Gln組和非Gln組感染性并發(fā)癥分別為9例、14例(P0.05),住院天數(shù)分別為(11.28±7.77)d、(12.03±9.02)d(P0.05)。NRS評(píng)分≥5分的病人,Gln組(130例)和非Gln組(47例)病人的并發(fā)癥分別為4例、6例,住院時(shí)間分別為(11.21±7.15)d、(12.73±1.26)d(P0.05)。多因素logistic回歸分析提示,Gln治療是感染性并發(fā)癥的保護(hù)因素,而NRS評(píng)分≥5分、術(shù)前GGT升高、術(shù)前前白蛋白降低是危險(xiǎn)因素,其OR值分別為0.76、1.19、1.25、1.39,P值均小于0.05。結(jié)論 Gln治療能顯著降低存在營(yíng)養(yǎng)風(fēng)險(xiǎn)肝膽外科手術(shù)病人的感染并發(fā)癥發(fā)生率,且NRS評(píng)分≥5分的病人尚可縮短住院時(shí)間,更能從Gln治療中獲益。
[Abstract]:Objective to observe the incidence of nutritional risk in patients undergoing hepatobiliary surgery and to explore the effect of glutamine Glutaminel (GLnn) treatment on the clinical outcome of patients with nutritional risk. The data of hepatobiliary surgery patients who were operated on from January 2011 to December 2014 in Wuhan General Hospital of Guangzhou military region were collected continuously and the NRS2002 score was used. A total of 402 patients were divided into Gln treatment group (248 cases) and non-#en1# group (154 cases). Results Infectious complications in Gln group and non-#en1# group were 9 cases or 14 cases respectively (P0.05). The days of hospitalization were 11.28 鹵7.77 days and 12.03 鹵9.02 days respectively. NRS score 鈮，

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