發(fā)布時(shí)間：2018-01-04 20:07

  本文關(guān)鍵詞：金葉敗毒顆粒輔助治療燒傷膿毒癥的臨床效果研究　出處：《中藥藥理與臨床》2016年06期 　論文類型：期刊論文

  更多相關(guān)文章： 金葉敗毒顆粒 膿毒癥 炎癥因子 腎臟功能

【摘要】：目的:觀察金葉敗毒顆粒佐治燒傷膿毒癥的臨床效果。方法:選取2013年2月至2014年2月我科室收治的燒傷并發(fā)膿毒癥患者45例,按隨機(jī)雙盲法將其分為對照組22例和觀察組23例。對照組給予常規(guī)治療,觀察組在對照組基礎(chǔ)上加用金葉敗毒顆粒。記錄并分析治療前和治療后10天兩組患者體溫、心率、白細(xì)胞、中性粒細(xì)胞、血尿素氮、血肌酐、腫瘤壞死因子(TNF-α)和白細(xì)胞介素-8(IL-8)的水平變化情況。結(jié)果:治療后觀察組患者體溫、心率分別為(37.2±0.4℃、85.5±5.1次/分),均明顯低于對照組(38.2±0.6℃、103.8±7.5次/分);觀察組治療后白細(xì)胞和中性粒細(xì)胞分別為(7.96±2.34×109/L、55.76±5.83%),均明顯低于對照組(14.28±3.61×109/L、69.46±7.15%);3觀察組治療后血尿素氮和血肌酐分別為(7.4±0.6mmol/L、90.1±2.2μmol/L),均明顯低于對照組(9.2±1.0mmol/L、95.7±3.3μmol/L);4觀察組治療后TNF-α和IL-8分別為(3.15±0.71ng/ml、3.01±0.42ng/ml),均明顯低于對照組(5.01±0.83ng/ml、4.19±0.53ng/ml)。結(jié)論:金葉敗毒顆�？烧{(diào)節(jié)燒傷膿毒癥患者的體溫和心率,維護(hù)腎臟功能,降低患者體內(nèi)炎癥水平。
[Abstract]:Objective: to observe the clinical effect of Jinye Baidu granule in treating burn sepsis. Methods: from February 2013 to February 2014, 45 burn patients with sepsis were selected. It was divided into control group (22 cases) and observation group (23 cases) according to random double blind method. The control group was given routine treatment. The observation group was treated with Jinye Baidu granule on the basis of the control group. The body temperature, heart rate, leukocyte, neutrophil, blood urea nitrogen and serum creatinine were recorded and analyzed before and 10 days after treatment. Results: after treatment, the temperature and heart rate of the patients in the observation group were 37.2 鹵0.4 鈩，

本文編號：1379887