【摘要】：在生物醫(yī)藥領(lǐng)域,通過(guò)對(duì)生物材料或活細(xì)胞進(jìn)行3D打印,可構(gòu)建復(fù)雜生物三維結(jié)構(gòu)如個(gè)性化植入體、可再生人工骨、體外細(xì)胞三維結(jié)構(gòu)體、人工器官等,因而基于生物3D打印在個(gè)性化定制及復(fù)雜結(jié)構(gòu)調(diào)控制造上的獨(dú)特優(yōu)勢(shì),綜述了生物3D打印技術(shù)的基本工藝、應(yīng)用領(lǐng)域與研究進(jìn)展.重點(diǎn)針對(duì)3D打印生物材料這一研究熱點(diǎn),全面討論了噴墨打印和注射擠出打印兩種路徑,分析總結(jié)了3D打印相關(guān)生物材料并應(yīng)用于體外模型、醫(yī)療器械和植入體的制造以及可降解組織支架、細(xì)胞三維結(jié)構(gòu)體的構(gòu)建,最后對(duì)該技術(shù)未來(lái)發(fā)展趨勢(shì)和研究重點(diǎn)提出展望.
[Abstract]:In the field of biomedicine, 3D printing of biomaterials or living cells can construct complex biological 3D structures such as personalized implantable, renewable artificial bone, in vitro cell 3D structure, artificial organ and so on. Therefore, based on the unique advantages of biological 3D printing in personalized customization and complex structure control manufacturing, the basic technology, application fields and research progress of biological 3D printing technology are reviewed. Aiming at the research hot spot of 3D printing biomaterials, two paths of inkjet printing and injection extrusion printing are discussed in detail, and the applications of 3D printing related biomaterials in vitro models, the manufacture of medical devices and implantable materials, the construction of degradable tissue scaffolds and cell 3D structures are analyzed and summarized. Finally, the future development trend and research emphasis of this technology are put forward.
【作者單位】： 上海理工大學(xué)材料科學(xué)與工程學(xué)院;
【基金】：上海理工大學(xué)科技發(fā)展基金資助項(xiàng)目(2016KJFZ011,2017KJFZ010)
【分類(lèi)號(hào)】：R318.08;TP391.73

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