數值模擬人內耳半規(guī)管膜迷路的機械壓痕實驗
[Abstract]:The mechanical indentation experiment was simulated numerically to study the displacement response of the labyrinth crest of the human semicircular canal membrane under the mechanical indentation excitation and to explore the relationship between the structure of the semicircular canal and the equilibrium mechanism. Based on the experimental data in literature, a three-dimensional elastohydrodynamic model of human semicircular canal membrane labyrinth was established, and the mechanical indentation process was numerically simulated by liquid-solid coupling method. The results show that under low frequency sinusoidal indentation loading (10/Hz), the crest displacement response induced by semicircular canal integration excitation is linearly correlated with the peak indentation peak, and the phase is the same. The lower the frequency of sinusoidal indentation in the low frequency range, the faster the peak displacement of horizontal semicircular canal crest becomes, the larger the attenuation ratio is, and the longer the stabilization time is. In this experiment, an effective liquid-solid coupling model of semicircular canal membrane labyrinth was established, and the quantitative relationship between mechanical indentation excitation and rotational excitation was described, which laid a foundation for further study of vestibular mechanics and understanding of equilibrium mechanism.
【作者單位】: 大連理工大學工業(yè)裝備結構分析國家重點實驗室;大連醫(yī)科大學第二臨床學院耳鼻咽喉科;
【基金】:國家自然科學基金項目(11072055,10902022,11032008) 遼寧省教育廳資助科研項目(L2012323)
【分類號】:R318.01
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