本文選題：嵌入式 + 血液粘度　； 參考：《北京工業(yè)大學(xué)》2012年碩士論文

【摘要】：人體的脈搏波中蘊(yùn)含著大量的心臟血管信息，脈搏波波形特征與血流動(dòng)力學(xué)參數(shù)的變化緊密相關(guān)，血流動(dòng)力學(xué)參數(shù)能直接反映心臟血管系統(tǒng)的功能狀態(tài)，利用檢測(cè)的心血管血流動(dòng)力學(xué)參數(shù)變化可以對(duì)心臟功能做出較為全面的評(píng)價(jià)。血液粘度是重要的心血管功能參數(shù)之一，目前臨床三高疾�。ǜ咧Y，高血壓病，糖尿�。┑牟±砘A(chǔ)都與血液粘度增高的血液流變學(xué)的異常改變有關(guān)。血液粘度升高導(dǎo)致血流緩慢,微循環(huán)功能發(fā)生障礙,組織器官缺血缺氧,最終導(dǎo)致心腦血管等循環(huán)系統(tǒng)疾患，因此血液粘度是評(píng)價(jià)這類疾病診治效果的重要依據(jù)之一。通過分析采集到的血流容積脈搏波來獲取粘度等心血管血流動(dòng)力學(xué)參數(shù)，在心血管疾病、妊娠期疾病的檢查、治療和康復(fù)評(píng)價(jià)上都具有十分重要的作用。嵌入式、便攜化的系統(tǒng)設(shè)計(jì)使得該研究在運(yùn)動(dòng)健身領(lǐng)域、家庭醫(yī)療方面也具有廣闊的運(yùn)用前景。 血液粘度無創(chuàng)檢測(cè)產(chǎn)品主要是通過脈搏波檢測(cè)技術(shù)來計(jì)算血液粘度值，以往的脈搏波波形采集和分析需要人為的干預(yù)，在采集過程中需人為的判波、選波和停止采集，自動(dòng)化程度低，操作繁瑣易引入人為因素的影響。目前市場(chǎng)上的脈搏波檢測(cè)設(shè)備受主控芯片運(yùn)算速度的限制，下位機(jī)采集的數(shù)據(jù)須送PC機(jī)進(jìn)行計(jì)算，隔離了系統(tǒng)的整體性。本文的研究目的是快速、方便、準(zhǔn)確的測(cè)得被測(cè)者血液粘度值等心血管參數(shù)，更好的為血流動(dòng)力學(xué)的進(jìn)一步科學(xué)研究奠定基礎(chǔ)。 本課題在心血管血流動(dòng)力學(xué)無創(chuàng)檢測(cè)理論基礎(chǔ)上，重新設(shè)計(jì)制作了新的血流傳感器，在血液粘度檢測(cè)上設(shè)計(jì)了新的采集和處理硬件電路，采用新的簡(jiǎn)單高效的波形提取算法和脈搏波波形質(zhì)量評(píng)價(jià)方法，提高了波形采集的質(zhì)量和準(zhǔn)確性，減少人為的干預(yù)，在電源供電上采用智能化的電源管理技術(shù)，節(jié)省電池的電量，延長(zhǎng)了系統(tǒng)的工作時(shí)間。充分利用數(shù)字信號(hào)處理器（DSP）高處理速度和低功耗特性，設(shè)計(jì)出功能全面、結(jié)構(gòu)小巧、抗干擾性強(qiáng)的血液粘度無創(chuàng)檢測(cè)設(shè)備，該設(shè)備能實(shí)現(xiàn)血流信號(hào)增益、基線的自動(dòng)調(diào)節(jié)、波形質(zhì)量實(shí)時(shí)評(píng)價(jià)、波形特征有效性判定、脈搏波特征自動(dòng)提取，并利用過采樣技術(shù)和無線數(shù)據(jù)傳輸技術(shù)實(shí)現(xiàn)操作的自動(dòng)化和智能化。本課題的設(shè)計(jì)意義是為心血管疾病檢查和治療提供科學(xué)合理的血流動(dòng)力學(xué)評(píng)價(jià)參數(shù)，提供一種便攜式的在體無創(chuàng)血液粘度檢測(cè)手段，在臨床和家庭保健領(lǐng)域提供客觀的評(píng)價(jià)意見和監(jiān)測(cè)技術(shù)。
[Abstract]:The pulse wave of human body contains a lot of information of heart blood vessel. The characteristics of pulse wave are closely related to the change of hemodynamic parameters. The hemodynamic parameters can directly reflect the functional state of heart vascular system. The changes of cardiovascular hemodynamic parameters can be used to evaluate cardiac function comprehensively. Blood viscosity is one of the important parameters of cardiovascular function. At present, the pathological basis of three clinical high diseases (hyperlipidemia, hypertension, diabetes mellitus) is related to the abnormal changes of hemorheology with high blood viscosity. The increase of blood viscosity leads to slow blood flow, dysfunction of microcirculation function, ischemia and hypoxia of tissues and organs, and eventually leads to circulatory diseases such as cardiovascular and cerebrovascular diseases. Therefore, blood viscosity is one of the important bases for evaluating the effect of diagnosis and treatment of these diseases. By analyzing the blood flow volume pulse wave to obtain the viscosity and other cardiovascular hemodynamic parameters, it plays a very important role in cardiovascular disease, gestational disease examination, treatment and rehabilitation evaluation. The embedded, portable system design makes the research has a broad application prospect in the field of sports and fitness, family medicine. Blood viscosity non-invasive testing products mainly calculate the value of blood viscosity through pulse wave detection technology. In the past, the acquisition and analysis of pulse wave waveforms need human intervention, and in the process of collection, it is necessary to judge, select and stop collecting waves. The degree of automation is low, the operation is cumbersome and easy to introduce the influence of human factors. At present, the pulse wave detection equipment in the market is limited by the operation speed of the main control chip, so the data collected by the lower computer must be sent to the PC for calculation, thus isolating the integrity of the system. The purpose of this paper is to quickly, conveniently and accurately measure the blood viscosity and other cardiovascular parameters, and lay a foundation for the further scientific research of hemodynamics. On the basis of the theory of non-invasive detection of cardiovascular hemodynamics, a new blood flow sensor is redesigned, and a new collection and processing hardware circuit is designed for the measurement of blood viscosity. New simple and efficient waveform extraction algorithm and pulse wave quality evaluation method are adopted to improve the quality and accuracy of waveform collection, reduce artificial intervention, and adopt intelligent power management technology in power supply. Saving battery power and prolonging the working time of the system. Making full use of the characteristics of high processing speed and low power consumption of digital signal processor (DSP), a non-invasive blood viscosity detecting device with comprehensive function, small structure and strong anti-interference is designed. The device can realize the automatic adjustment of blood flow signal gain and baseline. The real-time evaluation of waveform quality, the validity evaluation of waveform features, the automatic extraction of pulse wave features, and the use of over-sampling technology and wireless data transmission technology to realize the automation and intelligence of the operation. The design significance of this project is to provide scientific and reasonable hemodynamic evaluation parameters for the examination and treatment of cardiovascular diseases, and to provide a portable non-invasive blood viscosity measurement method in vivo. Provide objective evaluation and monitoring techniques in the field of clinical and family health care.
【學(xué)位授予單位】：北京工業(yè)大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2012
【分類號(hào)】：R318.6

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