本文選題：光電容積脈搏波 + 反射式測(cè)量��； 參考：《北京協(xié)和醫(yī)學(xué)院》2017年碩士論文

【摘要】：呼吸率是表征呼吸功能的的一個(gè)重要參數(shù),能夠提供與人體健康狀況相關(guān)的重要信息。持續(xù)、準(zhǔn)確的呼吸率監(jiān)測(cè)有助于預(yù)防和識(shí)別肺部、呼吸道等部位的病變。臨床上主要通過直接測(cè)量口部或鼻部的氣流,或者利用胸廓和腹部的運(yùn)動(dòng)檢測(cè),來實(shí)現(xiàn)對(duì)呼吸率的監(jiān)測(cè),這些檢測(cè)方式都具有一定的強(qiáng)迫性,并且設(shè)置繁瑣,不適于日常生活中使用。利用光電容積脈搏波方法進(jìn)行呼吸率提取,具有操作簡單、無創(chuàng)傷、適用性強(qiáng)等特點(diǎn)。因此實(shí)驗(yàn)室擬開發(fā)一種可穿戴式運(yùn)動(dòng)健康檢測(cè)設(shè)備,試圖通過3波長光電傳感裝置采集人體PPG信號(hào),進(jìn)而提取蘊(yùn)含的血氧和呼吸率等生理信息。本文圍繞設(shè)備的設(shè)計(jì)需求,進(jìn)行了兩方面的研究:為了研究從利用綠光為光源的PPG信號(hào)中提取呼吸率信息的可行性根據(jù)人體呼吸和光電容積波的作用規(guī)律,設(shè)計(jì)了以515nm綠光為光源的反射式脈搏信號(hào)檢測(cè)系統(tǒng),并與熱敏電阻采集的參考呼吸信號(hào)進(jìn)行對(duì)比測(cè)試實(shí)驗(yàn),獲得呼吸過慢、呼吸過速、自然呼吸3中呼吸狀態(tài)下的脈搏信號(hào)和同步的參開呼吸信號(hào),利用脈搏差分時(shí)間間隔算法提取呼吸率信息,通過統(tǒng)計(jì)學(xué)方法對(duì)數(shù)據(jù)進(jìn)行對(duì)比分析。結(jié)果表明,所設(shè)計(jì)脈搏呼吸頻率提取系統(tǒng)可以完成3種狀態(tài)下呼吸頻率提取,且與參考呼吸頻率具有良好的一致性。為了研究在較小的光源-檢測(cè)器間距下,紅光和紅外光在固定光學(xué)參數(shù)的生物組織模擬液中的穿透深度變化情況,以便為檢測(cè)探頭的設(shè)計(jì)提供參考,搭建了一套用于測(cè)量660nm紅光和940nm紅外光在均一生物組織模型中穿透深度的檢測(cè)系統(tǒng),實(shí)現(xiàn)在較小的光源-檢測(cè)器間距范圍內(nèi),定量地測(cè)量兩種波長的光在均一的生物組織模擬液中的穿透深度變化情況,測(cè)量結(jié)果為檢測(cè)探頭的設(shè)計(jì)提供了很好的參考數(shù)據(jù)。
[Abstract]:Respiratory rate is an important parameter to characterize respiratory function, which can provide important information related to human health. Continuous and accurate respiratory rate monitoring helps to prevent and identify lesions in the lungs, respiratory tract, etc. In clinic, the respiratory rate is monitored mainly by directly measuring the air flow in the mouth or nose, or by using the movement test of the chest and abdomen. These testing methods are all compulsive and cumbersome. Not suitable for daily use. The method of optoelectronic volumetric pulse wave is used to extract respiratory rate, which has the advantages of simple operation, no trauma and strong applicability. Therefore, the laboratory intends to develop a wearable exercise health detection device, which attempts to collect human PPG signals through a three-wavelength photoelectric sensor device, and then extract physiological information such as blood oxygen and respiration rate. In order to study the feasibility of extracting respiration rate information from PPG signal using green light as light source, according to the action law of human body respiration and photoelectric volume wave, this paper focuses on the design requirements of the equipment. A reflective pulse signal detection system with 515nm green light as light source is designed and compared with the reference respiration signal collected by thermistor. The pulse signal in the breathing state of natural respiration 3 and the synchronous parameterized respiration signal were extracted by using the pulse differential interval algorithm. The data were compared and analyzed by statistical method. The results show that the designed pulse respiratory frequency extraction system can extract the respiratory frequency in three states, and it is in good agreement with the reference respiratory frequency. In order to study the change of penetrating depth of red light and infrared light in biological tissue simulation solution with fixed optical parameters at small light-detector spacing, in order to provide reference for the design of detection probe, A detection system for measuring the penetration depth of 660nm red light and 940nm infrared light in a homogeneous biological tissue model is set up, which is realized in a small range of light-detector spacing. The change of penetration depth of two wavelengths of light in a homogeneous biological tissue simulation solution is quantitatively measured. The results provide a good reference data for the design of the probe.
【學(xué)位授予單位】：北京協(xié)和醫(yī)學(xué)院
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2017
【分類號(hào)】：TP274;R318

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