基于拉伸壓破試驗(yàn)的人體升主動(dòng)脈內(nèi)膜力學(xué)特性
發(fā)布時(shí)間:2018-05-08 12:19
本文選題:升主動(dòng)脈 + 壓破試驗(yàn); 參考:《北京工業(yè)大學(xué)學(xué)報(bào)》2017年07期
【摘要】:為獲取人體升主動(dòng)脈內(nèi)膜力學(xué)性質(zhì),利用單軸拉伸系統(tǒng),設(shè)計(jì)升主動(dòng)脈內(nèi)膜壓破及拉伸試驗(yàn)方案,獲取人體升主動(dòng)脈內(nèi)膜力學(xué)性質(zhì).研究結(jié)果表明:人體升主動(dòng)脈內(nèi)膜最大壓破力與厚度正相關(guān);內(nèi)膜的周向與縱向的應(yīng)力-應(yīng)變均呈非線性曲線關(guān)系,并存在各向異性,升主動(dòng)脈內(nèi)膜的縱向最大拉伸斷裂應(yīng)力大于周向,初始彈性模量分別為1 104、787 k Pa.因此,在對(duì)主動(dòng)脈內(nèi)膜破裂風(fēng)險(xiǎn)評(píng)估及建立主動(dòng)脈壁本構(gòu)方程時(shí)應(yīng)考慮厚度;在夾層、動(dòng)脈瘤擴(kuò)張初期,原發(fā)破口易沿縱向繼續(xù)撕裂.
[Abstract]:In order to obtain the mechanical properties of human ascending aorta intima, the uniaxial tension system was used to design the test scheme of ascending aortic intima pressure breaking and stretching, and the mechanical properties of human ascending aorta intima were obtained. The results show that the maximum pressure breaking force of human ascending aorta is positively correlated with the thickness of the intima, and the circumferential and longitudinal stress-strain curves of the intima are both nonlinear and anisotropic. The maximum longitudinal tensile fracture stress of ascending aortic intima is larger than that of circumferential direction, and the initial elastic modulus is 1 104787 KPA, respectively. Therefore, the thickness should be taken into account in assessing the risk of aortic intima rupture and establishing the aortic wall constitutive equation, and in the early stage of dissection and aneurysm dilatation, the primary rupture is prone to continue to tear along the longitudinal direction.
【作者單位】: 北京工業(yè)大學(xué)生命科學(xué)與生物工程學(xué)院;有研醫(yī)療器械(北京)有限公司;
【基金】:國(guó)家自然科學(xué)基金資助項(xiàng)目(11572014) 北京工業(yè)大學(xué)“智能制造領(lǐng)域大科研推進(jìn)計(jì)劃”資助項(xiàng)目
【分類號(hào)】:R318.01;R54
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