本文選題：機(jī)械性取栓 + 生物力學(xué)�。� 參考：《中國(guó)生物醫(yī)學(xué)工程學(xué)報(bào)》2014年01期

【摘要】：本研究模擬了兩款鎳鈦三維螺旋狀機(jī)械性取栓器(MERD)在徑向壓握、徑向釋放和血管內(nèi)遷移過(guò)程中的情況,并對(duì)單個(gè)模型結(jié)構(gòu)在各個(gè)接觸載荷下的力學(xué)性能進(jìn)行分析。建立了兩款機(jī)械性取栓器、壓握工具以及目標(biāo)血管的有限元模型。對(duì)圓柱狀壓握工具施加向內(nèi)的徑向位移UR=+0.9 mm,壓握取栓器至外徑為2.9 mm;將壓握工具恢復(fù)到原始尺寸,建立血管/取栓器接觸關(guān)系;牽引取栓器近頭端,使其在血管壁內(nèi)遷移滑動(dòng)。分析和比較兩款取栓器在壓握狀態(tài)下的徑向支撐力(RF)和最大主應(yīng)變(MPS)峰值,釋放狀態(tài)下變形血管的等效應(yīng)力峰值(VMS),遷移過(guò)程中取栓器的最大主應(yīng)變、血管壁的等效應(yīng)力峰值以及分析末期取栓器形態(tài)。結(jié)果表明,Ⅰ型和Ⅱ型取栓器的最大壓握主應(yīng)變峰值分別為3.23%和3.61%,Ⅰ型取栓器壓握過(guò)程更加安全;當(dāng)壓握外徑為3.0 mm時(shí),Ⅰ型取栓器的徑向支撐力為1.96 N,較Ⅱ型取栓器小21.6%,更容易壓握;Ⅰ型結(jié)構(gòu)在釋放和遷移的過(guò)程中,造成血管壁應(yīng)力集中的峰值分別為0.378 MPa和0.509 MPa,較Ⅱ型結(jié)構(gòu)大21.6%和30.5%。本研究結(jié)果可以用于螺旋狀機(jī)械性取栓器的結(jié)構(gòu)優(yōu)化設(shè)計(jì),提高其生物力學(xué)性能,在工程和臨床上具有重要應(yīng)用價(jià)值。
[Abstract]:In this study, two three dimensional helical nickel titanium bolt removers, MERD), were simulated during radial pressure grip, radial release and intravascular migration, and the mechanical properties of individual model structures under various contact loads were analyzed.Two finite element models of mechanical thrombolizer, gripper and target vessel were established.Apply an inward radial displacement of 0.9 mm to the cylindrical press grip tool, and 2.9 mm diameter to the external diameter of the pressure holder; restore the pressure grip tool to its original size and establish a vascular / latch contact relationship; pull the latch closer to the end of the head,Make it move and slide in the wall of the blood vessel.The peak values of radial support force (RFF) and maximum principal strain (MPS) of the two kinds of bolting devices under the pressure grip state were analyzed and compared. The peak equivalent stress of the deformed blood vessels in the release state was analyzed and compared. The maximum principal strain of the bolt extractor during the migration process was also analyzed and compared.The peak equivalent stress of the vessel wall and the morphology of the end-stage thrombectomy were analyzed.The results showed that the maximum principal strain of type 鈪，

本文編號(hào)：1771252