梅毒孕婦抗梅毒治療時機對新生兒梅毒感染的影響研究
發(fā)布時間:2019-08-13 08:26
【摘要】:目的探討梅毒孕婦抗梅毒治療時機對新生兒梅毒感染的影響,為先天性梅毒預防治療提供參考。方法選取2014年1月-2015年6月診治的妊娠期梅毒孕婦100例,根據(jù)治療時機分為早期組(孕周≤20周,63例)與晚期組(孕周20周,37例),均給予芐星青霉素治療,觀察妊娠結(jié)局、新生兒預后。結(jié)果早期組2例流產(chǎn)、2例早產(chǎn),早期組預后不良率為6.35%、足月分娩率為93.65%,晚期組流產(chǎn)2例、早產(chǎn)7例,晚期組預后不良率為24.32%、足月分娩率為85.68%,比較差異有統(tǒng)計學意義(P0.05);早期組分娩新生兒發(fā)生新生兒窒息4例、低體重4例、梅毒感染2例,發(fā)生率分別為6.35%、6.35%、3.17%,晚期組分娩新生兒發(fā)生新生兒窒息8例、低體重9例、梅毒感染8例,發(fā)生率分別為21.62%、24.32%、21.62%,比較差異有統(tǒng)計學意義(P0.05);早期組RPR滴度1:8、≥1:8的孕婦分娩新生兒分別有0例、2例為梅毒感染,梅毒感染率為0、3.17%,早期組RPR滴度1:8、≥1:8的孕婦分娩新生兒分別有1例、7例為梅毒感染,梅毒感染率為2.70%、18.92%,兩組RPR滴度1:8孕婦分娩新生兒梅毒感染率比較差異無統(tǒng)計學意義,RPR滴度≥1:8孕婦分娩新生兒梅毒感染率比較差異有統(tǒng)計學意義(P0.05)。結(jié)論梅毒孕婦抗梅毒治療時機越早新生兒梅毒感染率越低,妊娠結(jié)局及新生兒預后越好。
[Abstract]:Objective to investigate the effect of antisyphilis treatment time on neonatal syphilis infection in pregnant women with syphilis, and to provide reference for prevention and treatment of congenital syphilis. Methods from January 2014 to June 2015, 100 pregnant women with syphilis during pregnancy were divided into early group (gestational week 鈮,
本文編號:2525999
[Abstract]:Objective to investigate the effect of antisyphilis treatment time on neonatal syphilis infection in pregnant women with syphilis, and to provide reference for prevention and treatment of congenital syphilis. Methods from January 2014 to June 2015, 100 pregnant women with syphilis during pregnancy were divided into early group (gestational week 鈮,
本文編號:2525999
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