【摘要】：目的探討中老年人大皰性類天皰瘡(BP)合并臨床疾病的特點。方法收集2011年3月至2013年9月在該院門診就診及住院的BP及濕疹患者的臨床資料,對50例BP和49例濕疹患者的臨床資料進行比較分析。結(jié)果 BP平均發(fā)病年齡為73.5歲,診斷前病程平均3.4個月;老年濕疹發(fā)病平均年齡70.3歲,診斷前病程平均2.7個月,老年BP合并內(nèi)科疾病包括神經(jīng)系統(tǒng)疾病19例(38%),其中有腦血管病17例(腦血栓、腦出血、腦梗死等)和帕金森病1例、癡呆1例;高血壓7例(14%);糖尿病(DM)4例(8%);冠心病3例(6%);其他3例(6%)。老年濕疹伴發(fā)疾病包括:高血壓20例(40.8%);DM 8例(16.3%);冠心病7例(14%);腦血管疾病5例(10.2%);其他7例(14%)。結(jié)論老年人BP合并神經(jīng)系統(tǒng)疾病的情況較多見。二者合并出現(xiàn)的機制尚不清楚,免疫交叉反應(yīng)或與年齡相關(guān)的某些變性退化的過程可能激發(fā)BP的發(fā)病。老年人濕疹則合并高血壓、DM較多見,可能與體內(nèi)代謝及內(nèi)分泌變化及長期用降壓藥物及降糖藥物有關(guān)。
[Abstract]:Objective to investigate the clinical features of pemphigoid (BP) in middle-aged and elderly people. Methods from March 2011 to September 2013, the clinical data of 50 cases of BP and 49 cases of eczema were analyzed. The clinical data of BP and eczema patients who were treated and hospitalized in the hospital from March 2011 to September 2013 were collected. Results the mean age of onset of BP was 73. 5 years, and the mean course of disease was 3. 4 months before diagnosis. The average age of onset of eczema was 70.3 years old and the course of disease was 2.7months before diagnosis. 19 cases (38%) of senile BP complicated with internal diseases included nervous system diseases, among them 17 cases had cerebrovascular disease (cerebral thrombosis, cerebral hemorrhage). Cerebral infarction, etc.) and Parkinson's disease (1 case), dementia (1 case); There were 7 cases of hypertension (14%), 4 cases of diabetic (DM) (8%), 3 cases of coronary heart disease (6%) and 3 cases of others (6%). The concomitant diseases of eczema in the elderly included hypertension in 20 cases (40.8%); DM in 8 cases (16.3%), coronary heart disease in 7 cases (14%), cerebrovascular diseases in 5 cases (10.2%) and others in 7 cases (14%). Conclusion BP complicated with nervous system diseases is more common in the elderly. The mechanism of the combination is not clear, and the immune cross-reaction or some age-related degeneration processes may stimulate the pathogenesis of BP. Eczema is associated with hypertension in the elderly, and DM is more common, which may be related to metabolic and endocrine changes in the body and long-term use of antihypertensive drugs and hypoglycemic drugs.
【作者單位】： 鄂爾多斯市準格爾旗中蒙醫(yī)院皮膚科;吉林大學(xué)第二醫(yī)院;
【分類號】：R758.66

【共引文獻】

相關(guān)期刊論文 前10條

1 梁楊祖;周賢剛;;參芪五味子片治療心脾兩虛型失眠證的成本效果分析[J];中醫(yī)藥臨床雜志;2009年05期

2 周麗華;;自擬慢緊湯治療慢性緊張性頭痛療效觀察[J];中醫(yī)藥臨床雜志;2010年01期

3 劉毅斌;程紅亮;吳勁松;;針灸治療貝爾氏面癱75例時效性臨床研究[J];中醫(yī)藥臨床雜志;2010年03期

4 楊文明;李慶利;;活血化瘀法在急性腦出血治療中的地位與作用[J];中醫(yī)藥臨床雜志;2010年11期

5 鄧穎;袁昌文;;止癇湯治療難治性癲癇30例[J];中醫(yī)藥臨床雜志;2010年12期

6 王曉燕;;早期肢體康復(fù)訓(xùn)練對高血壓腦出血偏癱患者神經(jīng)功能的恢復(fù)作用[J];中醫(yī)藥臨床雜志;2011年12期

7 王曉e，

本文編號：2464407