【摘要】：目的探討食物特異性IgG4檢測在診斷并發(fā)胃腸道癥狀的食物過敏性濕疹患兒的應用價值。方法采用酶聯(lián)免疫吸附法(ELISA)對84例食物特異性Ig E篩查陰性的濕疹和慢性蕁麻疹患兒行食物特異性IgG4檢測。結果 84例患兒中,IgG4陽性75例(89.29%),1~4種過敏原及≥5種過敏原陽性者分別為17例、22例、13例、7例和16例。主要食物過敏原是牛奶和雞蛋,≤2歲和2歲患兒IgG4陽性率分別為90.00%(36/40)和88.63%(39/44),14種食物特異性IgG4的陽性率兩者差異無統(tǒng)計學意義(P0.05)。濕疹并發(fā)胃腸道癥狀組IgG4陽性率明顯高于濕疹無胃腸道癥狀組、蕁麻疹組和正常兒童組。蟹、牛奶、大麥、大豆、西紅柿的特異性IgG4的陽性率在各組間比較差異有統(tǒng)計學意義(P0.05)。結論并發(fā)胃腸道癥狀的濕疹患兒,檢測其食物特異性IgG4對其病因診斷及指導治療具有一定意義。
[Abstract]:Objective to investigate the value of food-specific IgG4 detection in the diagnosis of food allergic eczema in children with gastrointestinal symptoms. Methods 84 cases of food specific Ig E negative eczema and chronic urticaria were detected by enzyme-linked immunosorbent assay (ELISA). Food specific IgG4 was detected in 84 children with chronic urticaria and eczema. Results among the 84 cases, 75 cases (89.29%) were positive for IgG4, 17 cases were positive for 4 kinds of allergens and 鈮，

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