Semaphorin 5A在皮膚黑素瘤組織中的表達及與其惡性程度的相關性
發(fā)布時間:2019-03-16 11:53
【摘要】:目的觀察Semaphorin 5A在皮膚黑素瘤(CMM)組織中的表達情況,并探討其與CMM惡性程度的相關性。方法選擇20例CMM患者和20例黑素細胞痣者的石蠟包埋組織標本。CMM患者根據(jù)Clark(1969)分級方法,Ⅰ級3例(15.00%)、Ⅱ級3例(15.00%)、Ⅲ級4例(20.00%)、Ⅳ級7例(35.00%)、Ⅴ級有3例(15.00%)。免疫組化法檢測Semaphorin 5A在CMM及黑素細胞痣皮損組織中的表達,比較不同病理分級的CMM間Semaphorin 5A表達的差異。結果 Semaphorin 5A在CMM中的陽性表達率(80.00%,16/20)高于黑素細胞痣中的陽性表達率(5.00%,1/20)(P0.05);且Semaphorin 5A在CMM中的表達與Clark分級呈正相關(P0.05)。結論Semaphorin 5A在CMM組織中的表達升高,與CMM惡性程度有關。
[Abstract]:Objective to investigate the expression of Semaphorin 5A in cutaneous melanoma (CMM) and its correlation with the malignant degree of CMM. Methods paraffin embedded tissue samples of 20 patients with CMM and 20 patients with nevoid melanocytes were selected. According to Clark (1969) classification, 3 cases (15.00%) were grade 鈪,
本文編號:2441301
[Abstract]:Objective to investigate the expression of Semaphorin 5A in cutaneous melanoma (CMM) and its correlation with the malignant degree of CMM. Methods paraffin embedded tissue samples of 20 patients with CMM and 20 patients with nevoid melanocytes were selected. According to Clark (1969) classification, 3 cases (15.00%) were grade 鈪,
本文編號:2441301
本文鏈接:http://sikaile.net/yixuelunwen/pifb/2441301.html
最近更新
教材專著