尋常痤瘡對患者生活質(zhì)量和抑郁情緒影響的調(diào)查研究
發(fā)布時間：2019-02-27 16:37
【摘要】：目的了解尋常痤瘡對患者生活質(zhì)量和抑郁情緒的影響程度及相關(guān)因素,為綜合、系統(tǒng)地治療痤瘡、提高患者的生活質(zhì)量提供參考,同時也為制定有效的預防和干預措施提供科學依據(jù)。 方法選取2010年10月至2011年6月就診于中南大學湘雅三醫(yī)院皮膚科門診的尋常痤瘡患者作為調(diào)查對象,采用現(xiàn)場發(fā)放問卷方式進行調(diào)查。采用皮膚病生活質(zhì)量指數(shù)(DLQI)問卷評價過去一周內(nèi)痤瘡對患者生活質(zhì)量的影響,Beck抑郁問卷(BID)評價痤瘡患者的抑郁情緒嚴重程度,影響因素則通過自編問卷進行調(diào)查。使用Epidata3.1軟件建立數(shù)據(jù)庫,并采用SPSS16.0對資料進行統(tǒng)計分析,統(tǒng)計方法有統(tǒng)計描述、Spearman等級相關(guān)、Wilcoxon秩和檢驗,Kruskal-WallisH、多元回歸分析、無序多分類logistic回歸分析等。 結(jié)果 1.共發(fā)放調(diào)查問卷295份,回收有效問卷287份。其中男性100例(34.8%),女性187例(65.2%)；年齡為18-40歲,平均(22.49±3.96)歲；尋常痤瘡病情嚴重程度Ⅰ、Ⅱ、Ⅲ、Ⅳ級分別有165、56、38、28例,依次占57.5%、19.5%、13.2%、9.8%；病程為1個月～15年,平均(3.13±3.10)年。 2.287名尋常痤瘡患者DLQI生活質(zhì)量得分范圍為0-28分,平均5.28分,患者生活質(zhì)量的影響主要表現(xiàn)為疼痛或瘙癢、造成尷尬或自卑、影響社交休閑活動等。單因素分析顯示年齡、病情嚴重程度、病程與患者的生活質(zhì)量存在關(guān)系,而性別變量沒有影響；多元回歸分析結(jié)果表明,病情嚴重程度為患者生活質(zhì)量的影響因素。 3.287名尋常痤瘡患者的BDI抑郁總分為0～44分,平均8.55分。181例患者存在不同程度的抑郁(BDI總分≥5),檢出率為63.1%,其中輕度抑郁129例(44.9%)、中度抑郁28例(9.8%)、重度抑郁24例(8.4%)。抑郁情緒主要表現(xiàn)為憂愁、悲觀、對他人的興趣減少(社會退縮)等。 4.單因素分析顯示性別、痤瘡病情嚴重程度、痤瘡病程與患者的抑郁情緒存在關(guān)聯(lián),而年齡變量沒有影響；無序多分類logistic回歸分析結(jié)果顯示性別、病情嚴重程度、痤瘡病程與患者出現(xiàn)輕度和中重度抑郁情緒相關(guān)。 5.與尋常痤瘡患者出現(xiàn)輕度,中重度抑郁相關(guān)的因素都為性別、病情嚴重程度、病程,女性患者相對于男性患者更易出現(xiàn)輕度和中重度抑郁(OR=3.62與OR=2.63),隨著痤瘡病情的加重,患者出現(xiàn)輕度和中重度抑郁的風險也相應增加(OR=2.31與OR=4.51),病程在1-3年和3年及以上的患者相對于病程不滿1年的患者更容易出現(xiàn)輕度抑郁(OR=4.30與OR=7.44)。痤瘡病程在3年及以上的患者相對于病程不滿1年的患者更容易出現(xiàn)中重度抑郁(OR=3.60)。 結(jié)論 1.尋常痤瘡對患者的生活質(zhì)量造成了明顯的負面影響,主要表現(xiàn)為使患者出現(xiàn)疼痛或瘙癢癥狀、產(chǎn)生尷尬/自卑心理及影響其社交休閑活動等。 2.尋常痤瘡病情越嚴重,患者的生活質(zhì)量就越差。 3.尋常痤瘡患者大部分存在不同程度的抑郁,主要表現(xiàn)為憂愁、悲觀和社會退縮等心理。 4.患者病情越嚴重、病程越長及女性尋常痤瘡患者更易出現(xiàn)不同程度的抑郁。
[Abstract]:Objective To study the effect of common ulcers on the quality of life and the mood of depression, and to provide a reference for the comprehensive and systematic treatment of ulcers, to improve the quality of life of patients, and to provide scientific basis for the development of effective prevention and intervention measures. Methods From October 2010 to June 2011, the patients from the Department of Dermatology of the Department of Dermatology of the Third Xiangya Hospital of Central South University were selected as the subject of the investigation, and the site distribution questionnaire was used for the adjustment. A. The effect of pressure sore on the quality of life of patients over the past week was evaluated by using the quality index (DLQI) of the skin disease. The Beck Depression Questionnaire (BID) was used to evaluate the severity of depression in the patients with ulcers, and the influence factors were adjusted by the self-designed questionnaire. The data were analyzed by using the Epidata3.1 software, and the data were analyzed statistically by using the SPSS16.0. The statistical methods include statistical description, Spearman rank correlation, Wilcoxon rank sum test, Kruskal-Wallis, multiple regression analysis, and multi-classification logistic regression analysis. And the like. Results 1. A total of 295 questionnaires were distributed and the effective question was recovered. There were 287 males (34.8%),187 (65.2%) females,18 to 40 years of age, (22.49 to 3.96) years of age,165,56,38 and 28 cases of common aphtha, 57.5%, 19.5%, 13.2%, and 9.8%, respectively; and the course of the disease was 1. Monthly-15 years, average (3.13-3) (10) The life quality score of DLQI in 2.287 patients with common aphtha was 0-28, with an average of 5.28 points. The quality of life of the patient was mainly manifested as pain or itch, resulting in embarrassment or inferiority. Social leisure activities, etc. The single factor analysis showed that the age, the severity of the condition, the course of the disease and the quality of life of the patient were not affected, and the sex variable had no effect; and the multiple regression analysis showed that the severity of the condition was the patient's life. The total score of BDI in 3.287 patients with common aphtha was 0 to 44, with an average of 8.55.181 patients had different degrees of depression (BDI total score of 5). The positive rate was 63.1%. Among them,129 (44.9%) of the patients with mild depression,28 (9.8%) of moderate depression, and severe depression. 24 (8.4%). The mood of depression is mainly in the form of sadness, pessimism, and interest in others. Decrease (social withdrawal) and so on.4. The single factor analysis showed that the severity of the condition of sex and aphtha, the duration of the sore and the depressive mood of the patient were associated, and the age variable had no effect; the result of the multi-classification logistic regression analysis of the disorder showing the severity of sex, the severity of the condition, the duration of the sore and the light of the patient 5. The factors related to mild and moderate-to-severe depression in patients with common ulcers were gender, severity of the disease, course of disease, and mild and moderate-to-severe depression (OR = 3.62 and OR = 2) in female patients with respect to male patients. 63) The risk of mild and moderate-to-severe depression was also associated with increased risk of mild and moderate-to-severe depression in patients (OR = 2.31 and OR = 4.51), and mild depression was more likely to occur in patients with a course of 1-3 years and more than 3 years and above (OR = 4.30 and OR = 7.44). The duration of the sore is more likely to occur in patients with less than 3 years and above with respect to patients with less than 1 year of disease Severe Depression (OR = 3.60). Conclusion 1. The quality of life of patients with common aphtha has a significant negative effect on the quality of life of the patient, which is mainly manifested in the occurrence of pain or itching symptoms in the patient, and the occurrence of depression. To find and influence their social and leisure activities. The more severe the condition of the ulcers, the worse the quality of life of the patient. The more severe the patient is, the more serious the illness is.
【學位授予單位】：中南大學
【學位級別】：碩士
【學位授予年份】：2012
【分類號】：R758.733
本文編號：2431437
[Abstract]:Objective To study the effect of common ulcers on the quality of life and the mood of depression, and to provide a reference for the comprehensive and systematic treatment of ulcers, to improve the quality of life of patients, and to provide scientific basis for the development of effective prevention and intervention measures. Methods From October 2010 to June 2011, the patients from the Department of Dermatology of the Department of Dermatology of the Third Xiangya Hospital of Central South University were selected as the subject of the investigation, and the site distribution questionnaire was used for the adjustment. A. The effect of pressure sore on the quality of life of patients over the past week was evaluated by using the quality index (DLQI) of the skin disease. The Beck Depression Questionnaire (BID) was used to evaluate the severity of depression in the patients with ulcers, and the influence factors were adjusted by the self-designed questionnaire. The data were analyzed by using the Epidata3.1 software, and the data were analyzed statistically by using the SPSS16.0. The statistical methods include statistical description, Spearman rank correlation, Wilcoxon rank sum test, Kruskal-Wallis, multiple regression analysis, and multi-classification logistic regression analysis. And the like. Results 1. A total of 295 questionnaires were distributed and the effective question was recovered. There were 287 males (34.8%),187 (65.2%) females,18 to 40 years of age, (22.49 to 3.96) years of age,165,56,38 and 28 cases of common aphtha, 57.5%, 19.5%, 13.2%, and 9.8%, respectively; and the course of the disease was 1. Monthly-15 years, average (3.13-3) (10) The life quality score of DLQI in 2.287 patients with common aphtha was 0-28, with an average of 5.28 points. The quality of life of the patient was mainly manifested as pain or itch, resulting in embarrassment or inferiority. Social leisure activities, etc. The single factor analysis showed that the age, the severity of the condition, the course of the disease and the quality of life of the patient were not affected, and the sex variable had no effect; and the multiple regression analysis showed that the severity of the condition was the patient's life. The total score of BDI in 3.287 patients with common aphtha was 0 to 44, with an average of 8.55.181 patients had different degrees of depression (BDI total score of 5). The positive rate was 63.1%. Among them,129 (44.9%) of the patients with mild depression,28 (9.8%) of moderate depression, and severe depression. 24 (8.4%). The mood of depression is mainly in the form of sadness, pessimism, and interest in others. Decrease (social withdrawal) and so on.4. The single factor analysis showed that the severity of the condition of sex and aphtha, the duration of the sore and the depressive mood of the patient were associated, and the age variable had no effect; the result of the multi-classification logistic regression analysis of the disorder showing the severity of sex, the severity of the condition, the duration of the sore and the light of the patient 5. The factors related to mild and moderate-to-severe depression in patients with common ulcers were gender, severity of the disease, course of disease, and mild and moderate-to-severe depression (OR = 3.62 and OR = 2) in female patients with respect to male patients. 63) The risk of mild and moderate-to-severe depression was also associated with increased risk of mild and moderate-to-severe depression in patients (OR = 2.31 and OR = 4.51), and mild depression was more likely to occur in patients with a course of 1-3 years and more than 3 years and above (OR = 4.30 and OR = 7.44). The duration of the sore is more likely to occur in patients with less than 3 years and above with respect to patients with less than 1 year of disease Severe Depression (OR = 3.60). Conclusion 1. The quality of life of patients with common aphtha has a significant negative effect on the quality of life of the patient, which is mainly manifested in the occurrence of pain or itching symptoms in the patient, and the occurrence of depression. To find and influence their social and leisure activities. The more severe the condition of the ulcers, the worse the quality of life of the patient. The more severe the patient is, the more serious the illness is.
【學位授予單位】：中南大學
【學位級別】：碩士
【學位授予年份】：2012
【分類號】：R758.733
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