發(fā)布時(shí)間：2018-11-18 10:51

【摘要】：目的了解小汗腺汗孔癌的臨床特征及組織病理特點(diǎn)。方法對(duì)第四軍醫(yī)大學(xué)西京皮膚醫(yī)院2007年4月-2015年8月經(jīng)組織病理學(xué)檢查確診的5例小汗腺汗孔癌患者的臨床及組織病理特點(diǎn)進(jìn)行回顧性分析。結(jié)果 5例小汗腺汗孔癌患者中,男3例,女2例,平均年齡66.8歲,中位年齡69歲,平均病程1.5年。皮損部位:鼻部1例,顳部1例,下肢3例。臨床表現(xiàn)多為結(jié)節(jié)及斑塊,多數(shù)皮損伴有不同程度瘙癢、疼痛、糜爛及破潰。皮損組織病理可見(jiàn)排列緊密的團(tuán)塊狀嗜伊紅鱗狀樣細(xì)胞或基底樣細(xì)胞,分布不典型,團(tuán)塊中央可見(jiàn)導(dǎo)管分化結(jié)構(gòu),細(xì)胞異型性明顯。結(jié)論該病臨床表現(xiàn)無(wú)明顯特異性,確診需要依靠組織病理檢查。治療上應(yīng)早期予以手術(shù)切除皮損。若無(wú)轉(zhuǎn)移病灶則預(yù)后較好。
[Abstract]:Objective to investigate the clinical and histopathological features of eccrine sweat pore carcinoma. Methods the clinical and histopathological features of 5 patients with eccrine sweat pore carcinoma diagnosed by histopathological examination from April 2007 to August 2015 in Xijing skin Hospital of fourth military Medical University were retrospectively analyzed. Results among the 5 patients, there were 3 males and 2 females, with an average age of 66.8 years and a median age of 69 years, with an average course of 1.5 years. The lesions were nasal in 1 case, temporal in 1 case and lower extremity in 3 cases. Most of the lesions were associated with itching, pain, erosion and ulceration. Histopathology of lesions showed that there were dense clusters of eosinophilic squamous cells or basal cells with atypical distribution. The differentiation structure of ducts was seen in the center of the lumps and the heterogeneity of the cells was obvious. Conclusion there is no obvious specificity in clinical manifestation of the disease, and the diagnosis depends on histopathological examination. Early surgical excision of skin lesions should be performed on the treatment. If there were no metastatic lesions, the prognosis was better.
【作者單位】： 第四軍醫(yī)大學(xué)西京皮膚醫(yī)院;
【分類(lèi)號(hào)】：R739.5

【參考文獻(xiàn)】

相關(guān)期刊論文 前3條

1 吳亞桐;常建民;;小汗腺汗孔癌[J];臨床皮膚科雜志;2014年04期

2 趙菊平;祝宇;何z殉，

本文編號(hào)：2339830