【摘要】：目的評價口服特比萘芬聯(lián)合萘替芬酮康唑乳膏治療手足癬的臨床療效和安全性。方法將入選的168例手足癬患者隨機(jī)分成兩組,各84例。對照組予口服特比萘芬250mg,1次/d,治療組在對照組治療方案的基礎(chǔ)上予萘替芬酮康唑乳膏外搽,2~4次/d。兩組患者的療程均為1個月。結(jié)果治療組治療第1,2,3和4周末的有效率分別為22.62%,51.19%,80.95%和92.86%;對照組分別為14.29%,44.05%,67.86%和70.24%。有效率差異有統(tǒng)計(jì)學(xué)意義(P0.05)。兩組不良反應(yīng)均未予特殊處理,不影響治療。結(jié)論口服特比萘芬聯(lián)合萘替芬酮康唑乳膏治療手足癬的臨床療效顯著,不良反應(yīng)小,值得臨床選擇應(yīng)用。
[Abstract]:Objective to evaluate the efficacy and safety of terbinafine combined with ketoconazole cream in the treatment of tinea pedis. Methods 168 patients with tinea pedis were randomly divided into two groups, 84 cases in each group. The control group was given oral terbinafine 250 mg / d, and the treatment group was given nafenaphthene ketoconazole ointment 2 times / d 4 times per day on the basis of the control group's treatment plan. The course of treatment was 1 month in both groups. Results the effective rates of the treatment group at the end of the 1st week and the 4th week were 22.622.19% and 92.86%, respectively, while that of the control group were 14.292.05% and 70.24%, respectively. The difference of effective rate was statistically significant (P0.05). The adverse reactions in both groups were not specially treated and did not affect the treatment. Conclusion Oral terbinafine combined with natifen ketoconazole cream is effective in the treatment of tinea pedis.
【作者單位】： 山東省棗莊市皮膚病性病防治院;
【分類號】：R756.3

【相似文獻(xiàn)】

相關(guān)期刊論文 前10條

1 朱鐵君;特比萘芬短程療法治療手指甲癬[J];臨床皮膚科雜志;1994年04期

2 張愛軍,劉耿,王永賢,譚升順;特比萘芬治療甲癬的療效觀察[J];中國皮膚性病學(xué)雜志;1997年04期

3 虞瑞堯,薛文昌;特比萘芬與三唑類抗真菌藥治療甲癬的優(yōu)與劣[J];皮膚病與性病;1998年04期

4 曹來安;特比萘芬與咪康唑外用治療嬰幼兒皮膚粘膜念珠菌病的比較[J];中國麻風(fēng)皮膚病雜志;2001年01期

5 邵永山,任虹,解春桃,余展國;特比萘芬治療兒童頭癬13例[J];中國麻風(fēng)皮膚病雜志;2001年04期

6 李連平,王云,丁淑娟;特比萘芬治療真菌皮膚病的臨床療效[J];實(shí)用醫(yī)藥雜志;2005年05期

7 楊發(fā)枝,唐寧,粟玉珍,于淞;特比萘芬治療孢子絲菌病[J];臨床皮膚科雜志;1999年01期

8 李大寧,陳德利;應(yīng)用國產(chǎn)與進(jìn)口特比萘芬治療甲真菌病患者的療效/費(fèi)用分析[J];中國麻風(fēng)皮膚病雜志;2000年02期

9 吳汝英,艾蕾,喬桂芝;復(fù)方特比萘芬凝膠治療手足癬的臨床觀察[J];中國麻風(fēng)皮膚病雜志;2002年02期

10 賈四友;;特比萘芬乳膏治療皮膚淺部真菌病168例[J];中國麻風(fēng)皮膚病雜志;2006年09期

相關(guān)會議論文 前10條

1 高露娟;余進(jìn);矢口貴志;陳偉;李若瑜;;特比萘芬成功治愈誤診為曲霉感染的皮膚利什曼病1例[A];2011全國中西醫(yī)結(jié)合皮膚性病學(xué)術(shù)會議論文匯編[C];2011年

2 王愛平;高那;劉偉;萬U，

本文編號：2200567