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叢狀柵欄狀有包膜神經(jīng)瘤

發(fā)布時間:2018-06-15 16:23

  本文選題:神經(jīng)瘤 + 有包膜; 參考:《臨床皮膚科雜志》2017年12期


【摘要】:報告1例叢狀柵欄狀有包膜神經(jīng)瘤。患者男,42歲。右口角外側(cè)丘疹8年。皮膚科檢查:右口角外側(cè)一膚色丘疹,質(zhì)中,表面光滑。皮損組織病理:真皮內(nèi)可見多個腫瘤團塊,境界清楚,瘤團內(nèi)梭形細(xì)胞增生,其間可見較多裂隙,瘤團外層細(xì)胞呈柵欄狀排列,細(xì)胞異形性不明顯。免疫病理:增生的梭形瘤細(xì)胞S-100蛋白陽性,腫瘤細(xì)胞間可見散在神經(jīng)纖維絲蛋白(NFPR)陽性的神經(jīng)軸突,腫瘤周圍可見上皮膜抗原(EMA)弱陽性的不完整的包膜。診斷:叢狀柵欄狀有包膜神經(jīng)瘤。
[Abstract]:A case of plexiform palisade capsular neuroma was reported. The patient was 42 years old. Right angle lateral papules for 8 years. Dermatology examination: a skin papules on the lateral side of the right horn, medium, smooth surface. Histopathology of the lesions: there were many tumor masses in the dermis. The boundary was clear. The spindle cells in the tumor masses were proliferated and there were many cracks in them. The outer cells of the tumor masses were arranged in a palisade shape, and the cell heterogeneity was not obvious. The immunopathology showed that S-100 protein was positive in proliferative spindle tumor cells, the axons of neurofibronectin (NFPRP) -positive were seen between tumor cells, and the incomplete capsule with weak positive epithelium membrane antigen (EMA) was found around the tumor. Diagnosis: plexiform palisade with capsular neuroma.
【作者單位】: 第四軍醫(yī)大學(xué)西京皮膚醫(yī)院;西安市長慶油田職工醫(yī)院皮膚科;
【分類號】:R739.5

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