天堂国产午夜亚洲专区-少妇人妻综合久久蜜臀-国产成人户外露出视频在线-国产91传媒一区二区三区

Th1,Th2,Th17及Treg與尋常型天皰瘡的相關(guān)性

發(fā)布時(shí)間:2018-06-10 11:14

  本文選題:天皰瘡 + Th細(xì)胞; 參考:《中國(guó)皮膚性病學(xué)雜志》2016年06期


【摘要】:目的探討Th1,Th2,Th17和Treg細(xì)胞與尋常型天皰(PV)發(fā)病的相關(guān)性。方法天皰瘡患者29例(活動(dòng)組18例,緩解組11例),對(duì)照組14例,采用流式細(xì)胞術(shù)檢測(cè)外周血Th1,Th2,Treg和Th17細(xì)胞占CD4~+T淋巴細(xì)胞的比例,用SPSS17.0統(tǒng)計(jì)軟件進(jìn)行統(tǒng)計(jì)分析。結(jié)果活動(dòng)組PV的Th17細(xì)胞百分比(6.73±2.29)%顯著高于緩解組(3.08±0.91)%和對(duì)照組(0.18±0.10)%(P0.05);緩解組PV的Th17細(xì)胞百分比高于對(duì)照組(P0.05);PV活動(dòng)組(1.70±0.87)%、緩解組(1.28±0.58)%和對(duì)照組(1.46±0.63)%,三組間的Treg細(xì)胞百分比差異無統(tǒng)計(jì)學(xué)意義(P0.05);顒(dòng)組PV的Th1細(xì)胞百分比(8.68±1.77)%低于對(duì)照組(12.29±1.57)%和緩解組(10.88±2.98)%(P0.05),Th1細(xì)胞在對(duì)照組與緩解組PV中的差異無統(tǒng)計(jì)學(xué)意義(P0.05)。PV活動(dòng)組Th2細(xì)胞百分比(2.86±0.79)%高于對(duì)照組(0.41±0.39)%和緩解組(0.99±0.45)%(P0.05),緩解組的Th2細(xì)胞高于對(duì)照組(P0.05)。結(jié)論天皰瘡患者外周血Th17,Th2細(xì)胞表達(dá)升高,Th1細(xì)胞表達(dá)降低,Treg細(xì)胞表達(dá)無異常。Th1,Th2和Th17細(xì)胞可能參與了天皰瘡的發(fā)病過程。
[Abstract]:Objective to investigate the correlation between Th1, Th2, Th17 and Treg cells and the onset of pemphigus vulgaris (PV). Methods 29 patients with pemphigus (18 in the active group, 11 in the remission group) and 14 in the control group were examined by flow cytometry to detect the proportion of Th1, Th2, Treg and Th17 cells to CD4~+T lymphocytes, and the statistical analysis was carried out by SPSS17.0 statistical software. The percentage of Th17 cells in group PV (6.73 + 2.29)% was significantly higher than that in the remission group (3.08 + 0.91)% and the control group (0.18 + 0.10)% (P0.05), and the percentage of Th17 cells in the remission group was higher than that in the control group (P0.05), the PV activity group (1.70 + 0.87)%, the remission group (1.28 + 0.58)% and the control group (1.46 + 0.63)%, and there was no significant difference in the percentage of Treg cells between the three groups (P0.05). The percentage of Th1 cells in the active group PV (8.68 + 1.77)% was lower than that of the control group (12.29 + 1.57)% and remission group (10.88 + 2.98)% (P0.05). There was no significant difference between the Th1 cells in the control group and the remission group (P0.05).PV activity group (2.86 + 0.79)% (0.41 + 0.39)% and remission group (0.41 + 0.39)% (0.99 + 0.45)% (P0.05), and Th2 in the remission group. The cells were higher than the control group (P0.05). Conclusion the expression of Th17, Th2 cells in the peripheral blood of pemphigus patients increased, the expression of Th1 cells decreased, and the expression of Treg cells had no abnormal.Th1. Th2 and Th17 cells may be involved in the pathogenesis of pemphigus.
【作者單位】: 昆明醫(yī)科大學(xué)第二附屬醫(yī)院風(fēng)濕免疫科;勝利油田中心醫(yī)院皮膚科;
【基金】:云南省聯(lián)合專項(xiàng)基金(2012FB059)
【分類號(hào)】:R758.66
,

本文編號(hào):2003018

資料下載
論文發(fā)表

本文鏈接:http://sikaile.net/yixuelunwen/pifb/2003018.html


Copyright(c)文論論文網(wǎng)All Rights Reserved | 網(wǎng)站地圖 |

版權(quán)申明:資料由用戶f289e***提供,本站僅收錄摘要或目錄,作者需要?jiǎng)h除請(qǐng)E-mail郵箱bigeng88@qq.com
亚洲一区二区三区三州| 亚洲国产av一二三区| 欧美午夜性刺激在线观看| 中文字字幕在线中文乱码二区| 日韩精品一级片免费看| 欧美黑人暴力猛交精品| 中文字幕亚洲精品人妻| 老司机精品视频在线免费看| 国产性情片一区二区三区| 亚洲精品欧美精品日韩精品| 夫妻性生活黄色录像视频| 免费高清欧美一区二区视频| 亚洲精品伦理熟女国产一区二区| 五月激情综合在线视频| 国产精品福利一二三区| 深夜福利欲求不满的人妻| 丰满人妻一二区二区三区av| 黄片在线观看一区二区三区| 91日韩在线视频观看| 亚洲精品国男人在线视频| 搡老妇女老熟女一区二区| 日本熟妇五十一区二区三区| 91偷拍与自偷拍精品| 亚洲一区二区三区熟女少妇| 国产视频一区二区三区四区| 国产在线日韩精品欧美| 一区二区三区日韩中文| 欧美做爰猛烈叫床大尺度| 欧美日韩综合综合久久久| 成年人视频日本大香蕉久久| 欧美一区二区在线日韩| 国产精品亚洲一级av第二区| 99香蕉精品视频国产版| 伊人网免费在线观看高清版 | 在线欧洲免费无线码二区免费| 在线视频三区日本精品| 亚洲中文字幕亲近伦片| 久久精品少妇内射毛片| 不卡中文字幕在线视频| 最近中文字幕高清中文字幕无| 爽到高潮嗷嗷叫之在现观看|