本文選題：甲真菌病 + 致病真菌　； 參考：《吉林大學》2012年碩士論文

【摘要】：目的： 了解吉林省甲真菌病病原菌的種類和構(gòu)成，以便指導(dǎo)臨床采取針對性的治療、提高療效。 方法： 對自2011年3月至2012年2月，在吉林大學第二醫(yī)院皮膚科門診就診的100例具有典型甲真菌病臨床表現(xiàn)，且鏡檢陽性患者的臨床資料及真菌培養(yǎng)結(jié)果進行分析。并應(yīng)用SPSS統(tǒng)計軟件進行分析比較。 結(jié)果： 臨床分型：遠端側(cè)位甲下型病甲(DLSO)203個，占60.1%，全甲損毀型病甲(TDO)89個，占26.3%，白色淺表型病甲(SWO)39個，占11.5%，近端甲下型病甲(PSO)7個，占2.1%。共分離培養(yǎng)出致病真菌51株,皮膚癬菌28株(占54.9%),其中紅色毛癬菌26株(占51%),酵母菌22株(占43.1%),Geomyces sp.1株占(2%)。 結(jié)論： 1、吉林省甲真菌病病原菌主要為皮膚癬菌,其中紅色毛癬菌最多見，酵母菌比例較吉林省之前調(diào)查結(jié)果明顯增高。 2、吉林省甲真菌病臨床類型以遠端側(cè)位甲下型甲真菌病最為多見，全甲損毀型甲真菌病次之。 3、趾甲發(fā)病率明顯高于指甲的發(fā)病率。 4、拇指病甲、拇趾病甲發(fā)病率明顯高于其它甲。 5、發(fā)病年齡以中青年較為多見，男女發(fā)病無明顯差異。 6、經(jīng)北京大學第一醫(yī)院真菌研究中心鑒定，，此次調(diào)查中發(fā)現(xiàn)一新的菌株Geomyces sp.，關(guān)于其致病性尚需進一步研究。
[Abstract]:Objective: To understand the species and composition of the pathogenic bacteria of onychomycosis in Jilin province in order to guide the clinical treatment and improve the curative effect. Methods: From March 2011 to February 2012, 100 patients with typical onychomycosis in Department of Dermatology, second Hospital of Jilin University were studied. The clinical data and fungal culture results of positive patients were analyzed. And the SPSS statistical software was used to analyze and compare. Results: Clinical classification: DLSO (60.1%), TDO9 (26.3cm), SWO (39 cases), PSO (2.7%) and PSO7 (2.1%) in distal lateral hypothyroidism (DLSO) and proximal hypothyroidism (PSO7), with a total of 26. 3% (26. 3%), 39 (11. 5%) in superficial white armour, and 7 (2. 1%) in proximal hypothyroidism (PSO). A total of 51 strains of pathogenic fungi were isolated, 28 strains of dermatophytes (54.9%), 26 strains of Trichophyton rubrum (51%) and 22 strains of yeast (43.1%) were isolated and cultured. Conclusion: 1. The main pathogenic bacteria of onychomycosis in Jilin Province were dermatophytes, among which Trichophyton rubrum was the most common, and the proportion of yeast was higher than that of Jilin Province. 2. The most common clinical types of onychomycosis in Jilin Province were distal subnail onychomycosis, followed by total nail lesion onychomycosis. 3. The incidence of toenail was significantly higher than that of nail. 4. The incidence of thumb and hallucinosis was significantly higher than that of others. 5. The age of onset was more common in young and middle age, and there was no significant difference between male and female. 6. A new strain of Geomyces sp. was identified by the Fungi Research Center of the first Hospital of Peking University. The pathogenicity of the strain remains to be further studied.
【學位授予單位】：吉林大學
【學位級別】：碩士
【學位授予年份】：2012
【分類號】：R756.4

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