本文選題：太田痣 + 調(diào)Q開關(guān)Nd��； 參考：《昆明醫(yī)科大學(xué)》2017年碩士論文

【摘要】：[目的]:觀察云南地區(qū)170例太田痣患者發(fā)病特征,回顧性調(diào)查Q開關(guān)Nd:YAG 1064nm激光治療療效和不良反應(yīng)。[方法]:收集2011年1月至2014年1月在昆明醫(yī)科大學(xué)第一附屬醫(yī)院皮膚科首診并接受調(diào)Q開關(guān)Nd:YAG 1064nm激光治療的云南地區(qū)太田痣患者170例,對(duì)其發(fā)病特點(diǎn)、激光療效、影響療效的相關(guān)因素、術(shù)后不良反應(yīng)及復(fù)發(fā)等情況以問卷形式隨訪并進(jìn)行臨床分析。[結(jié)果]:受調(diào)查患者男女比例為1:3.72。29例患者出生即有(17.06%),兒童期發(fā)病多見(67.06%),部分青春期發(fā)病(27.06%)。雙側(cè)患病者占3.53%。男性發(fā)病高峰出現(xiàn)在嬰兒期:0-1歲,女性發(fā)病的兩個(gè)高峰分別是0-3歲、10-18歲。所有患者治療1-6次,治療4次時(shí),患者和醫(yī)生評(píng)價(jià)的總有效率分別為79.99%、80%;治療6次時(shí),患者和醫(yī)生評(píng)價(jià)的總有效率分別為97.84%、97.85%;不同治療次數(shù)療效差異有統(tǒng)計(jì)學(xué)意義(P0.001)。治療4次時(shí),褐色皮損患者療效優(yōu)于藍(lán)黑色皮損患者(P0.05) ; Tanino分型中Ⅰ、Ⅱ型患者療效優(yōu)于其他分型(P0.05);病程小于10年的患者療效優(yōu)于病程大于10年的患者(P0.05)。首次治療年齡≤1歲者療效優(yōu)于1-10歲者,1-10歲者療效優(yōu)于10-20歲者,10-20歲者療效優(yōu)于20歲者,四者差異有顯著性(P0.05);隨訪半年以上,術(shù)后不良反應(yīng)的發(fā)生率為16.47%,三島分型Ⅱ型更易發(fā)生色素沉著;隨著治療次數(shù)增加,色沉風(fēng)險(xiǎn)同時(shí)也增加。復(fù)發(fā)率為6.47%,發(fā)病年齡越早越容易復(fù)發(fā)。[結(jié)論]:就診的云南地區(qū)太田痣患者的男女比例、發(fā)病年齡等發(fā)病臨床特征與其他地區(qū)不盡相同,但趨勢(shì)相似。使用調(diào)Q開關(guān)Nd:YAG1064nm激光治療太田痣安全有效,術(shù)后不良反應(yīng)及復(fù)發(fā)發(fā)生率低�；颊咧委煷螖�(shù)越多,痊愈率越高;褐色皮損及Tanino分型Ⅰ、Ⅱ型患者療效更優(yōu);患者首次治療年齡越小,病程越短,治療相同次數(shù)所達(dá)到的總有效率越高,因此越早進(jìn)行激光治療,療效越好。
[Abstract]:Objective: to observe the clinical characteristics of 170 patients with nevus of Ota in Yunnan, and to investigate retrospectively the curative effect and adverse reaction of Q-switch Nd:YAG 1064nm laser. Methods: a total of 170 patients with nevus of Ota in Yunnan were first diagnosed and treated with Q-switched Nd:YAG 1064nm laser from January 2011 to January 2014 in Department of Dermatology, first affiliated Hospital of Kunming Medical University. The related factors influencing the curative effect, postoperative adverse reaction and recurrence were followed up by questionnaire and clinical analysis. [results]: the ratio of male to female was 1: 3.72.29 cases. There were 17.06 cases at birth, 67.06% in childhood and 27.06% in part of puberty. Patients with bilateral disease accounted for 3.53%. The highest incidence occurred in males aged 0-1 years in infancy, and the two peaks in females were 0-3 years and 10-18 years old respectively. All the patients were treated 1-6 times and 4 times, the total effective rate of patients and doctors were 79.99 and 800.The total effective rates of patients and doctors were 97.84 and 97.855.There was significant difference in the curative effect of different treatment times (P 0.001). After 4 times of treatment, the curative effect of brown lesions was better than that of blue-black lesions (P0.05), the efficacy of type 鈪，

本文編號(hào)：1933192